Literature DB >> 6177792

Localization of antigenic determinants of a viral protein by inhibition of enzyme-linked immunosorbent assay (ELISA) with tryptic peptides.

D Altschuh, M H Van Regenmortel.   

Abstract

A new method is described for localizing antigenic determinants in globular proteins by means of inhibition of enzyme-linked immunosorbent assay (ELISA) with tryptic peptides. The inhibitory activity of 10 tryptic peptides of the coat protein of 2 strains of tobacco mosaic virus (TMV) was demonstrated by inhibition of ELISA and verified by inhibition of complement fixation tests. These results bring to 7 the number of antigenic determinants of TMV protein that have been defined.

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Year:  1982        PMID: 6177792     DOI: 10.1016/0022-1759(82)90307-6

Source DB:  PubMed          Journal:  J Immunol Methods        ISSN: 0022-1759            Impact factor:   2.303


  6 in total

Review 1.  Protein antigenicity.

Authors:  M H Van Regenmortel
Journal:  Mol Biol Rep       Date:  1992-06       Impact factor: 2.316

2.  Influence of high hydrostatic pressure on epitope mapping of tobacco mosaic virus coat protein.

Authors:  Daniel Ferreira de Lima Neto; Carlos Francisco Sampaio Bonafe; Clarice Weis Arns
Journal:  Viral Immunol       Date:  2014-03       Impact factor: 2.257

3.  Immunological properties and biological function of monoclonal antibodies to tobacco mosaic virus.

Authors:  R G Dietzgen
Journal:  Arch Virol       Date:  1986       Impact factor: 2.574

Review 4.  The antigenicity of tobacco mosaic virus.

Authors:  M H Van Regenmortel
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  1999-03-29       Impact factor: 6.237

5.  A major part of the polypeptide chain of tobacco mosaic virus protein is antigenic.

Authors:  Z A Moudallal; J P Briand; M H Regenmortel
Journal:  EMBO J       Date:  1985-05       Impact factor: 11.598

6.  Monoclonal antibodies as probes of the antigenic structure of tobacco mosaic virus.

Authors:  Z Al Moudallal; J P Briand; M H Van Regenmortel
Journal:  EMBO J       Date:  1982       Impact factor: 11.598

  6 in total

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