beta 2 Microglobulin in lichen planus.

The aim of the present study was to examine idiopathic lichen planus for possible changes in the serum concentration of the immunological marker beta 2 microglobulin (beta 2m), a component of HLA antigens. It was shown that serum levels of beta 2m were not different in lichen planus from those in controls. Although these findings do not support major systemic immunopathological changes in lichen planus, they do not exclude the involvement of local immune mechanisms.