Literature DB >> 6177587

Effect of highly selective vagotomy on pancreatic exocrine function and on cholecystokinin and gastrin release.

N I Ramus, R C Williamson, J M Oliver, D Johnston.   

Abstract

The effect of highly selective vagotomy on pancreatic exocrine function and the release of gastrin and cholecystokinin was studied in 10 patients with endoscopically-proven duodenal ulceration. Cholecystokinin and gastrin concentrations in serum both increased significantly after highly selective vagotomy. Amylase concentration in the duodenal aspirate increased significantly after vagotomy, but trypsin concentration remained unchanged. The expected reductions in gastric acid secretion were noted. Thus highly selective vagotomy reduces acid secretion effectively in patients with duodenal ulcer without impairing the exocrine function of the pancreas.

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Year:  1982        PMID: 6177587      PMCID: PMC1419780          DOI: 10.1136/gut.23.7.553

Source DB:  PubMed          Journal:  Gut        ISSN: 0017-5749            Impact factor:   23.059


  35 in total

Review 1.  Gastrointestinal hormones: some thoughts about clinical applications.

Authors:  M I Grossman
Journal:  Scand J Gastroenterol       Date:  1972       Impact factor: 2.423

2.  Gallbladder volume and contractility after truncal, selective and highly selective (parietal-cell) vagotomy in man.

Authors:  G J Parkin; R B Smith; D Johnston
Journal:  Ann Surg       Date:  1973-11       Impact factor: 12.969

3.  Altered pancreatic and biliary function after vagotomy and pyloroplasty.

Authors:  J R Malagelada; V L Go; W H Summerskill
Journal:  Gastroenterology       Date:  1974-01       Impact factor: 22.682

4.  Vagotomy and the external function of the pancreas.

Authors:  J Kramhöft; I Balslev; F Lindahl; O G Backer
Journal:  Scand J Gastroenterol       Date:  1974       Impact factor: 2.423

5.  Influence of chronic administration of pentagastrin on the pancreas in hypophysectomized rats.

Authors:  P D Mayston; J A Barrowman
Journal:  Gastroenterology       Date:  1973-03       Impact factor: 22.682

6.  Gall-bladder function after vagotomy.

Authors:  J Tinker; A G Cox
Journal:  Br J Surg       Date:  1969-10       Impact factor: 6.939

7.  Highly selective vagotomy without a drainage procedure in the treatment of duodenal ulcer.

Authors:  D Johnston; A R Wilkinson
Journal:  Br J Surg       Date:  1970-04       Impact factor: 6.939

8.  Influence of parietal cell vagotomy and selective gastric vagotomy on gastric emptying rate and serum gastrin concentration.

Authors:  O Brandsborg; M Brandsborg; N A Lovgreen; K Mikkelsen; B Moller; M Rokkjaer; E Amdrup
Journal:  Gastroenterology       Date:  1977-02       Impact factor: 22.682

9.  Faecal fat excretion and stool colour after vagotomy and pyloroplasty.

Authors:  C Wastell; H Ellis
Journal:  Br Med J       Date:  1966-05-14

10.  Vagotomy without diarrhoea.

Authors:  D Johnston; C S Humphrey; B E Walker; C N Pulvertaft; J C Goligher
Journal:  Br Med J       Date:  1972-09-30
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  3 in total

Review 1.  Laboratory tests in the diagnosis of the chronic pancreatic diseases. Part 2. Tests of pancreatic secretion.

Authors:  E J Boyd; K G Wormsley
Journal:  Int J Pancreatol       Date:  1987-08

2.  Relationship between gastric emptying of a solid meal and emptying of the gall bladder before and after vagotomy.

Authors:  J N Baxter; J S Grime; M Critchley; S A Jenkins; R Shields
Journal:  Gut       Date:  1987-07       Impact factor: 23.059

Review 3.  Gallbladder motility, gallstones, and the surgeon.

Authors:  R Patankar; M M Ozmen; I S Bailey; C D Johnson
Journal:  Dig Dis Sci       Date:  1995-11       Impact factor: 3.199

  3 in total

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