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Literature DB >> 6177220

Species and tissue differences of histamine storage and release.

Abstract

Histamine release by compound 48/80 was studied in vivo and in vitro in different tissues of the cat and rat. A good correlation was fond between both kinds of experiment. The histamine stores in the cat salivary gland are poorly sensitive to this histamine-liberating substance. In vitro studies with heart and lungs of the rat and guinea pig showed no correlation between the spontaneous histamine release and the release induced by compound 48/80. This finding suggests the existence of two pools of tissue histamine, both with different storage and release properties, and most probably with different functions in the body.

Entities: Chemical Species

Mesh：

Substances：

Year: 1982 PMID： 6177220 DOI： 10.1007/BF01965110

Source DB: PubMed Journal: Agents Actions ISSN： 0065-4299

33 in total

Review 6. Histamine: entering physiology.

Authors: G Kahlson; E Rosengren
Journal: Experientia Date: 1972-09-15

7. Nonmast-cell histamine kinetics--II. Effect of histidine decarboxylase inhibitors on rates of decline of tissue 3H-histamine in the female rat.

Authors: H L Johnson
Journal: Biochem Pharmacol Date: 1969-03 Impact factor: 5.858

Species and tissue differences of histamine storage and release.

1. Evidence for non-mast cell histamine in the vascular wall.

2. Mechanism of histamine release in mast cells.

3. Isolation of "biologically intact" mast cells.

4. A comparison of the effects of anaphylactic shock and of chemical histamine releasers.

5. The isolation and some properties of guinea pig mesenteric mast cells.

Review 6. Histamine: entering physiology.

7. Nonmast-cell histamine kinetics--II. Effect of histidine decarboxylase inhibitors on rates of decline of tissue 3H-histamine in the female rat.

8. Isolation and some properties of mast cells from the mesentery of the rat and guinea pig.

9. Release of histamine by substance P.

10. Histamine release from mast cells by physiologically occurring substances.

1. Comparative studies of mast cells from normal (non-immunized) and actively sensitized dogs.

2. The role of tissue mast cells in exocrine secretion: studies in the submandibular gland of the cat.

3. Different responses of rodent mast cells to lysophosphatidylserine.

4. Histamine-releasing properties of mast cells from various strains of mice.