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Literature DB >> 6177207

The role of N-acetyl-neuraminic acid in the triggering of rat mast cells by polycationic molecules.

Abstract

Three substances known to act on N-acetylneuraminic acid (NANA), were tested for their activity on rat peritoneal mast cells. Both neuraminidase, which splits off NANA, and the lectin from Cepaea nemoralis directed against NANA are histamine releasers. Periodate itself did not trigger the cells but inhibited the releasing action of other substances. The results provide further evidence for the role of NANA in the triggering of mast cells. A cytotoxic substance, benzyl-polyethylene imine, triggers mast cells without affecting NANA. In addition, the role of histamine-BSA conjugates as histamine releasers is described.

Entities: Chemical Species

Mesh：

Substances：

Year: 1982 PMID： 6177207 DOI： 10.1007/BF01965118

Source DB: PubMed Journal: Agents Actions ISSN： 0065-4299

13 in total

1. Isolation of "biologically intact" mast cells.

Authors: B UVNAS; I L THON
Journal: Exp Cell Res Date: 1959-11 Impact factor: 3.905

2. [Serologic peculiarities of a heterophilic receptor from duck blood cells].

Authors: G Uhlenbruck; G I Pardoe
Journal: Z Naturforsch B Date: 1969-01 Impact factor: 1.047

3. On the nature of the presumed receptor for IgE on mast cells. I. The effect of sialidase and phospholipase C treatment on the capacity of rat peritoneal cells to participate in IgE-mediated, antigen-induced histamine release in vitro.

Authors: M K Bach; J R Brashler
Journal: J Immunol Date: 1973-06 Impact factor: 5.422

7. Histamine release from rat mast cells induced by the lectin from the snail, Cepaea nemoralis L. - a counterpart to the triggering action of polycations?

Authors: S Schnitzler
Journal: Acta Histochem Date: 1982 Impact factor: 2.479

The role of N-acetyl-neuraminic acid in the triggering of rat mast cells by polycationic molecules.

1. Isolation of "biologically intact" mast cells.

2. [Serologic peculiarities of a heterophilic receptor from duck blood cells].

3. On the nature of the presumed receptor for IgE on mast cells. I. The effect of sialidase and phospholipase C treatment on the capacity of rat peritoneal cells to participate in IgE-mediated, antigen-induced histamine release in vitro.

Review 4. [Immunobiology of neuraminic acid: a contribution to the antigenicity of brain tumors].

5. Protein purification by affinity chromatography. Derivatizations of agarose and polyacrylamide beads.

6. [Purification and properties of the haemagglutinins anti-AcN and anti-AcA (author's translation)].

7. Histamine release from rat mast cells induced by the lectin from the snail, Cepaea nemoralis L. - a counterpart to the triggering action of polycations?

Review 8. Mechanisms of histamine release in anaphylactic and anaphylactoid reactions.

9. Histamine release from rat mast cells induced by protamine sulfate and polyethylene imine.

10. Induction of histamine secretion by polycations.

1. Lectin binding sites in Paramecium tetraurelia cells. I. Labeling analysis predominantly of secretory components.