Literature DB >> 6177039

Suicide transport: destruction of neurons by retrograde transport of ricin, abrin, and modeccin.

R G Wiley, W W Blessing, D J Reis.   

Abstract

Certain toxic lectins, including ricin, are retrogradely transported along neuronal processes to the cell body where they inactivate ribosomes, resulting in neuronal death. This process of "suicide transport" suggests a powerful new experimental strategy for solving neurobiological problems.

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Year:  1982        PMID: 6177039     DOI: 10.1126/science.6177039

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  21 in total

1.  Response of adult cat abducens internuclear interneurons to selective removal of their target motoneurons.

Authors:  R R De la Cruz; R Baker; J M Delgado-García
Journal:  Exp Brain Res       Date:  1991       Impact factor: 1.972

Review 2.  Plant as a plenteous reserve of lectin.

Authors:  A G Ingale; A U Hivrale
Journal:  Plant Signal Behav       Date:  2013-10-01

3.  Effects of retrograde axonal transport of Ricinus communis agglutinin I on neuroma formation.

Authors:  I Nennesmo; K Kristensson
Journal:  Acta Neuropathol       Date:  1986       Impact factor: 17.088

4.  Central projection of rat sciatic nerve fibres as revealed by Ricinus communis agglutinin and horseradish peroxidase tracers.

Authors:  S K Leong; C K Tan
Journal:  J Anat       Date:  1987-10       Impact factor: 2.610

Review 5.  Recent advances in the use of selective neuron-destroying agents for neurobiological research.

Authors:  A Contestabile; P Migani; A Poli; L Villani
Journal:  Experientia       Date:  1984-06-15

6.  Afferents to different layers of the dorsolateral isocortex in rats.

Authors:  I Divac; J Regidor; S Milosevic; J Mogensen; K Zilles
Journal:  Anat Embryol (Berl)       Date:  1995-07

7.  Infiltration of carbon-labelled monocytes into the dorsal motor nucleus following an intraneural injection of ricinus communis agglutinin-60 into the vagus nerve in rats.

Authors:  E A Ling; S K Leong
Journal:  J Anat       Date:  1988-08       Impact factor: 2.610

8.  Diphtheria toxin mutant selectively kills cerebellar Purkinje neurons.

Authors:  C J Riedel; K M Muraszko; R J Youle
Journal:  Proc Natl Acad Sci U S A       Date:  1990-07       Impact factor: 11.205

9.  Amyotrophic lateral sclerosis with marked neurological asymmetry: clinicopathological study.

Authors:  Y Mochizuki; T Mizutani; T Takasu
Journal:  Acta Neuropathol       Date:  1995       Impact factor: 17.088

10.  Cytotoxic effects of adriamycin on mouse hypoglossal neurons following retrograde axonal transport from the tongue.

Authors:  L Bigotte; Y Olsson
Journal:  Acta Neuropathol       Date:  1983       Impact factor: 17.088

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