Literature DB >> 6176653

A monoclonal antibody directed against the HLA-Bw6 epitope.

S F Radka, D D Kostyu, D B Amos.   

Abstract

A cytotoxic monoclonal antibody, SFR8-B6, produced by immunizing KGH rats with partially purified glycoprotein from JY, a human B lymphoblastoid cell line, detects HLA-Bw6, a unique public antigen on the HLA-B molecule. By cytotoxicity, SFR8-B6 has complete concordance with the presence of Bw6 as defined by alloantisera, and its reactivity segregates with HLA in families. Because sera detecting Bw4 and Bw6 are rare, this monoclonal antibody has value as a perpetual standard. In addition, SFR8-B6 offers potential as a probe for investigating the molecular relationships of HLA antigens.

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Year:  1982        PMID： 6176653

Source DB:  PubMed          Journal:  J Immunol        ISSN： 0022-1767            Impact factor:   5.422


  28 in total

1.  Definition of epitopes on HLA class I molecules by polyclonal antipeptide sera.

Authors:  M Bouillot; J Choppin; J P Levy
Journal:  Immunogenetics       Date:  1990       Impact factor: 2.846

2.  A transposable epitope of HLA-B7, B40 molecules.

Authors:  J P Ways; D A Lawlor; A M Wan; P Parham
Journal:  Immunogenetics       Date:  1987       Impact factor: 2.846

3.  Definition of the HLA-A29 peptide ligand motif allows prediction of potential T-cell epitopes from the retinal soluble antigen, a candidate autoantigen in birdshot retinopathy.

Authors:  F Boisgerault; I Khalil; V Tieng; F Connan; T Tabary; J H Cohen; J Choppin; D Charron; A Toubert
Journal:  Proc Natl Acad Sci U S A       Date:  1996-04-16       Impact factor: 11.205

4.  Expression of an HLA-Bw6-related specificity by the HLA-Cw3 molecule.

Authors:  C Layet; T Delovitch; P Ferrier; D H Caillol; B R Jordan; F A Lemonnier
Journal:  Immunogenetics       Date:  1985       Impact factor: 2.846

5.  A transcriptome-proteome integrated network identifies endoplasmic reticulum thiol oxidoreductase (ERp57) as a hub that mediates bone metastasis.

Authors:  Naiara Santana-Codina; Rafael Carretero; Rebeca Sanz-Pamplona; Teresa Cabrera; Emre Guney; Baldo Oliva; Philippe Clezardin; Omar E Olarte; Pablo Loza-Alvarez; Andrés Méndez-Lucas; Jose Carlos Perales; Angels Sierra
Journal:  Mol Cell Proteomics       Date:  2013-04-26       Impact factor: 5.911

6.  Transfection of murine LMTK- cells with purified HLA class I genes. VII. Association of allele- and locus-specific serological reactivities with respectively the first and second domains of the HLA-B7 molecule.

Authors:  R Sodoyer; B Kahn-Perles; T Strachan; J Sire; M J Santoni; C Layet; P Ferrier; B R Jordan; F A Lemonnier
Journal:  Immunogenetics       Date:  1986       Impact factor: 2.846

7.  Identification of the amino acid residues defining an intralocus determinant in the alpha 1 domain of HLA-A molecules.

Authors:  F Lozano; J Santos-Aguado; L Borche; L Places; N Doménech; A Gayá; R Vilella; J Vives
Journal:  Immunogenetics       Date:  1989       Impact factor: 2.846

8.  Serological demonstration of HLA-Bw4/Bw6 epitopes on hybrid molecules between HLA-B35 and HLA-B51.

Authors:  M Sekimata; H Hayashi; S Nakayama; K Kano; M Takiguchi
Journal:  Immunogenetics       Date:  1989       Impact factor: 2.846

9.  Quantitative correlation between HLA class I allele expression and recognition of melanoma cells by antigen-specific cytotoxic T lymphocytes.

Authors:  L Rivoltini; K C Barracchini; V Viggiano; Y Kawakami; A Smith; A Mixon; N P Restifo; S L Topalian; T B Simonis; S A Rosenberg
Journal:  Cancer Res       Date:  1995-07-15       Impact factor: 12.701

10.  Discriminating virulence mechanisms among Bacillus anthracis strains by using a murine subcutaneous infection model.

Authors:  Hitendra S Chand; Melissa Drysdale; Julie Lovchik; Theresa M Koehler; Mary F Lipscomb; C Rick Lyons
Journal:  Infect Immun       Date:  2008-11-03       Impact factor: 3.441
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