| Literature DB >> 6176557 |
Abstract
Ketotifen-induced histamine release from human leucocytes is independent of extracellular calcium and does not require metabolic energy. Furthermore, histamine release is accompanied by a loss of cellular cytoplasmic contents. This suggests that the mechanism of ketotifen-induced histamine release at high concentrations is non-specific and is similar to that of clemastine, a typical H1 antagonist.Entities:
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Year: 1982 PMID： 6176557 DOI： 10.1159/000233090
Source DB: PubMed Journal: Int Arch Allergy Appl Immunol ISSN： 0020-5915