Literature DB >> 6175521

Detection of lung cancer with 55Co-bleomycin using a positron camera. A comparison with 57Co-bleomycin and 55Co-bleomycin single photon scintigraphy.

O E Nieweg, H Beekhuis, A M Paans, D A Piers, W Vaalburg, J Welleweerd, T Wiegman, M G Woldring.   

Abstract

57-Co-bleomycin is useful in the detection and staging of lung cancer, but the long half-life of 57Co (270 days) has discouraged its widespread acceptance. We investigated the shorter living positron emitting 55Co (half-life 18.2 h) as a level for bleomycin. In eleven patients with proven lung cancer scintigraphy with 55Co-bleomycin, using a positron camera, demonstrated the tumor in ten cases. Tumor to lung ratios were calculated. The results were superior to those obtained with 55Co-bleomycin single photon imaging but inferior to those obtained with 57Co-bleomycin scintigraphy.

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Year:  1982        PMID： 6175521     DOI： 10.1007/BF00256396

Source DB:  PubMed          Journal:  Eur J Nucl Med        ISSN： 0340-6997


  9 in total

1.  Chemotherapeutic drugs marked with radioactive isotopes.

Authors:  O Monod; M Rymer
Journal:  Cancer Chemother Rep 3       Date:  1973-03

2.  Distribution of labeled bleomycin in normal and tumor-bearing mice.

Authors:  R B Grove; W C Eckelman; R C Reba
Journal:  J Nucl Med       Date:  1973-12       Impact factor: 10.057

3.  [Co 57 labelled bleomycin. Its value in the diagnosis of malignant tumors and of their extensions].

Authors:  J P Nouel; H Renault; J Robert; C Jeanne; L Wicart
Journal:  Nouv Presse Med       Date:  1972-01-08

4.  Cobalt-labeled bleomycin--a new radiopharmaceutical for tumor localization. A comparative clinical evaluation with gallium citrate.

Authors:  K P Poulose; A E Watkins; R C Reba; W C Eckelman; M Goodyear
Journal:  J Nucl Med       Date:  1975-09       Impact factor: 10.057

5.  Some experience with 57Co-labeled bleomycin as a tumor-seeking agent.

Authors:  J J Rasker; A M Poll; H Beekhuis; M G Woldring; H O Nieweg
Journal:  J Nucl Med       Date:  1975-11       Impact factor: 10.057

6.  Iodinated bleomycin: an unsatisfactory radiopharmaceutical for tumor localization.

Authors:  W C Eckelman; H Kubota; B A Siegel; T Komai; W J Rzeszotarski; R C Reba
Journal:  J Nucl Med       Date:  1976-05       Impact factor: 10.057

7.  Clinical evaluation of radiolabeled bleomycin (BLEO) for tumor detection.

Authors:  R B Grove; R C Reba; W C Eckelman; M Goodyear
Journal:  J Nucl Med       Date:  1974-06       Impact factor: 10.057

8.  Clinical evaluation of radio-labelled bleomycin for tumor detection.

Authors:  J J Rasker; H Beekhuis; M A van de Poll; A Versluis; H Jurjens; M G Woldring
Journal:  Nuklearmedizin       Date:  1978-12       Impact factor: 1.379

9.  Cobalt-57-bleomycin scanning of hila and mediastinum in patients with bronchial carcinoma: a prospective study.

Authors:  J J Rasker; H Beekhuis; A M van de Wal; J N Homan van der Heide; M G Woldring
Journal:  Thorax       Date:  1976-12       Impact factor: 9.139
  9 in total
  3 in total

1.  57Co-bleomycin and 67Ga-citrate in detecting and staging lung cancer.

Authors:  O E Nieweg; H Beekhuis; D A Piers; H J Sluiter; A M van der Wal; M G Woldring
Journal:  Thorax       Date:  1983-01       Impact factor: 9.139

Review 2.  Radioimmunoimaging with longer-lived positron-emitting radionuclides: potentials and challenges.

Authors:  Tapan K Nayak; Martin W Brechbiel
Journal:  Bioconjug Chem       Date:  2009-05-20       Impact factor: 4.774

3.  Yields of Photo-Proton Reactions on Nuclei of Nickel and Separation of Cobalt Isotopes from Irradiated Targets.

Authors:  Andrey G Kazakov; Julia S Babenya; Taisya Y Ekatova; Sergey S Belyshev; Vadim V Khankin; Alexander A Kuznetsov; Sergey E Vinokurov; Boris F Myasoedov
Journal:  Molecules       Date:  2022-02-24       Impact factor: 4.411
  3 in total

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