| Literature DB >> 6175439 |
H Bringel, C Vela, V Ureña, D Gurbindo, R Garcia, C Lahoz.
Abstract
Sera from 177 atopic patients treated by immunotherapy were screened in order to detect IgD antibodies against a purified fraction of Lollium perenne (fractions C). IgD antibodies were found in 23% of the subjects. Eight of these sera were selected and their IgD isolated by means of immunoabsorption. The in vitro biological activity of the IgD antibodies against fraction C was tested by three methods: basophil degranulation, histamine release and RAST inhibition test. In all these assays, the data obtained indicated a possible blocking effect of the IgD antibodies upon the IgE in vitro mediated reactions.Entities:
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Year: 1982 PMID： 6175439 DOI： 10.1111/j.1365-2222.1982.tb03124.x
Source DB: PubMed Journal: Clin Allergy ISSN： 0009-9090