Literature DB >> 6175312

Genetic analysis of human salivary alpha-amylase isozymes by isoelectric focusing.

P D Eckersall, J A Beeley.   

Abstract

The isozymes of human salivary alpha-amylase have been separated by thin-layer gel isoelectric focusing in a pH 4-8 gradient followed by a starch-iodine zymogram procedure. The normal isozyme pattern (N) consisted of five major isozymes together with a number of minor ones. In addition, seven variant isozyme phenotypes were also observed, which had a combined frequency of 11.7% in a random population of 368 individuals. Analysis of familial data is indicative of the inheritance of autosomal codominant alleles.

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Year:  1981        PMID： 6175312     DOI： 10.1007/BF00484564

Source DB:  PubMed          Journal:  Biochem Genet        ISSN： 0006-2928            Impact factor:   1.890


  8 in total

1.  Methods for collecting individual components of mixed saliva: the relevance to clinical pharmacology.

Authors:  K W Stephen; C F Speirs
Journal:  Br J Clin Pharmacol       Date:  1976-04       Impact factor: 4.335

2.  A rapid technique for the detection of amylase isoenzymes using an enzyme sensitive "test-paper".

Authors:  P E Burdett; A E Kipps; P H Whitehead
Journal:  Anal Biochem       Date:  1976-05-07       Impact factor: 3.365

Review 3.  The human alpha-amylases.

Authors:  A D Merritt; R C Karn
Journal:  Adv Hum Genet       Date:  1977

4.  Human salivary amylase: genetics of electrophoretic variants.

Authors:  J C Ward; A D Merritt; D Bixler
Journal:  Am J Hum Genet       Date:  1971-07       Impact factor: 11.025

5.  The heritability of human salivary isoamylases.

Authors:  R O Wolf; L L Taylor; J D Niswander; J T Schwartz
Journal:  Arch Oral Biol       Date:  1971-11       Impact factor: 2.633

6.  An improved procedure for isoelectric focusing of human salivary proteins.

Authors:  P D Eckersall; R J Mairs; J A Beeley
Journal:  Arch Oral Biol       Date:  1981       Impact factor: 2.633

7.  Polymorphism of human salivary amylase: a preliminary communication.

Authors:  K de Soyza
Journal:  Hum Genet       Date:  1978-12-18       Impact factor: 4.132

8.  New genetic variants of parotid salivary amylase.

Authors:  J C Pronk; R R Frants
Journal:  Hum Hered       Date:  1979       Impact factor: 0.444
  8 in total
  2 in total

1.  Variation in gene copy number and polymorphism of the human salivary amylase isoenzyme system in Caucasians.

Authors:  R A Bank; E H Hettema; M A Muijs; G Pals; F Arwert; D I Boomsma; J C Pronk
Journal:  Hum Genet       Date:  1992-05       Impact factor: 4.132

2.  Study of the ultrastructure of Enterococcus faecalis and Streptococcus mutans incubated with salivary antimicrobial peptides.

Authors:  Blanca Blancas; María de Lourdes Lanzagorta; Luis Felipe Jiménez-Garcia; Reyna Lara; José Luis Molinari; Ana María Fernández
Journal:  Clin Exp Dent Res       Date:  2021-05-05
  2 in total

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