| Literature DB >> 6175045 |
Abstract
A range of membrane-active drugs were tested for their ability to prevent beta-thromboglobulin and platelet factor 4 release from freshly collected blood platelets. While all the drugs tested could inhibit collagen-induced platelet aggregation, only a few, notably procaine and the anti-malarial drugs chloroquine, hydroxychloroquine, camoquine and quinacrine (mepacrine), effectively prevented the alpha-granule release reaction.Entities:
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Year: 1982 PMID： 6175045 DOI： 10.1016/0049-3848(82)90241-9
Source DB: PubMed Journal: Thromb Res ISSN： 0049-3848 Impact factor: 3.944