Literature DB >> 6173760

Molecular cloning establishes proenkephalin as precursor of enkephalin-containing peptides.

U Gubler, P Seeburg, B J Hoffman, L P Gage, S Udenfriend.   

Abstract

Molecular cloning and DNA sequencing have yielded considerable structural information about proenkephalin. All previously characterized intermediate peptides of the enkephalin pathways in bovine adrenal medulla have now been aligned into an unambiguous primary structure. Two basic amino acid residues serve as processing signals for release of each of the different components.

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Year:  1982        PMID： 6173760     DOI： 10.1038/295206a0

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   49.962


  75 in total

1.  Immunohistochemical localization of opioid peptides in the brain of the leech Theromyzon tessulatum.

Authors:  M Verger-Bocquet; J Malecha; G Tramu
Journal:  Cell Tissue Res       Date:  1987-10       Impact factor: 5.249

2.  A new splice of life for the μ-opioid receptor.

Authors:  Michael J Iadarola; Matthew R Sapio; Andrew J Mannes
Journal:  J Clin Invest       Date:  2015-05-26       Impact factor: 14.808

3.  Differential accessibilities of dibasic prohormone processing sites of proenkephalin to the aqueous environment revealed by H-D exchange mass spectrometry.

Authors:  Weiya D Lu; Kyle Asmus; Shin-Rong Hwang; Sheng Li; Virgil L Woods; Vivian Hook
Journal:  Biochemistry       Date:  2009-02-24       Impact factor: 3.162

4.  Enkephalin convertase localization by [3H]guanidinoethylmercaptosuccinic acid autoradiography: selective association with enkephalin-containing neurons.

Authors:  D R Lynch; S M Strittmatter; S H Snyder
Journal:  Proc Natl Acad Sci U S A       Date:  1984-10       Impact factor: 11.205

Review 5.  Brain-specific aminopeptidase: from enkephalinase to protector against neurodegeneration.

Authors:  Koon-Sea Hui
Journal:  Neurochem Res       Date:  2007-05-03       Impact factor: 3.996

6.  Processing of enkephalin-containing peptides in isolated bovine adrenal chromaffin granules.

Authors:  G Fleminger; E Ezra; D L Kilpatrick; S Udenfriend
Journal:  Proc Natl Acad Sci U S A       Date:  1983-10       Impact factor: 11.205

7.  Proenkephalin, [Met]enkephalin, and oxytocin immunoreactivities are colocalized in bovine hypothalamic magnocellular neurons.

Authors:  J J Vanderhaeghen; F Lotstra; D R Liston; J Rossier
Journal:  Proc Natl Acad Sci U S A       Date:  1983-08       Impact factor: 11.205

8.  Carboxypeptidase B-like converting enzyme activity in secretory granules of rat pituitary.

Authors:  V Y Hook; Y P Loh
Journal:  Proc Natl Acad Sci U S A       Date:  1984-05       Impact factor: 11.205

9.  Intrinsic GABAergic system of adrenal chromaffin cells.

Authors:  Y Kataoka; Y Gutman; A Guidotti; P Panula; J Wroblewski; D Cosenza-Murphy; J Y Wu; E Costa
Journal:  Proc Natl Acad Sci U S A       Date:  1984-05       Impact factor: 11.205

10.  Linear and accurate quantitation of proenkephalin-derived peptides by isotopic labeling with internal standards and mass spectrometry.

Authors:  Steven J Bark; Weiya D Lu; Vivian Hook
Journal:  Anal Biochem       Date:  2009-03-14       Impact factor: 3.365
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