Literature DB >> 6173748

Effect of human leukocyte interferon on human lymphocytes in vitro: cytogenetic studies.

J P Sørensen, M K Jensen, C Jersild.   

Abstract

Mitogen-stimulated lymphocytes from 8 healthy donors were exposed to interferon, and cytogenetic studies were preformed. The response of lymphocytes to the mitogens phytohemagglutinin (PHA), concanavalin A (con A) and pokeweed mitogen (PWM) was inhibited by interferon, whereas an increased number of structural chromosomal aberrations was not detected. Further investigations of the cytogenetic effects of interferon are needed.

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Year:  1981        PMID: 6173748     DOI: 10.1016/0165-1218(81)90077-x

Source DB:  PubMed          Journal:  Mutat Res        ISSN: 0027-5107            Impact factor:   2.433


  2 in total

1.  Alpha-interferon and fragility at 16q22. A study on 15 selected controls and 146 selected patients.

Authors:  F Shabtai; J Orlyn; J Hart; S Bichacho; I Halbrecht
Journal:  Hum Genet       Date:  1987-01       Impact factor: 4.132

2.  Familial fragility on chromosome 16 (fra 16q22) enhanced by both interferon and Distamycin A.

Authors:  F Shabtai; D Klar; S Bichacho; J Hart; I Halbrecht
Journal:  Hum Genet       Date:  1983       Impact factor: 4.132

  2 in total

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