| Literature DB >> 6173467 |
Abstract
A rapid and highly sensitive procedure for simultaneous determination of serotonin, 5-hydroxyindoleacetic acid, 3,4-dihydroxyphenylacetic acid and homovanillic acid is described. After precipitation of proteins with perchloric acid the samples are applied directly to a high performance liquid chromatograph, with electrochemical detection. As little as 20 pg of serotonin, 5-hydroxyindoleacetic acid, and 3,4-dihydroxyphenylacetic acid and 200 pg of homovanillic acid can be detected. One chromatographic run requires less than 10 min.Entities:
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Year: 1982 PMID: 6173467 DOI: 10.1111/j.1471-4159.1982.tb08708.x
Source DB: PubMed Journal: J Neurochem ISSN: 0022-3042 Impact factor: 5.372