Literature DB >> 6173316

The participation of trimethylammonium in the mouse erythrocyte epitope recognized by monoclonal autoantibodies.

D Serban, J M Pages, A E Bussard, I P Witz.   

Abstract

Monoclonal IgM anti-erythrocyte autoantibody produced by a NZB-derived hybridoma has been found to react with trimethylammonium-containing compounds. Such compounds are able to prevent the lysis of bromelain-treated mouse erythrocytes (BrMRBC) by those autoantibodies. Using a column of insolubilized betaine hydrazine (BH) the monoclonal anti-erythrocyte antibody has been specifically retained. Elution of this antibody was accomplished by 0.15 M choline (Ch).

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Year:  1981        PMID: 6173316     DOI: 10.1016/0165-2478(81)90012-2

Source DB:  PubMed          Journal:  Immunol Lett        ISSN: 0165-2478            Impact factor:   3.685


  2 in total

1.  Phospholipid epitopes for mouse antibodies against bromelain-treated mouse erythrocytes.

Authors:  S Kawaguchi
Journal:  Immunology       Date:  1987-09       Impact factor: 7.397

2.  Autoantibodies against mouse bromelain-modified RBC are specifically inhibited by a common membrane phospholipid, phosphatidylcholine.

Authors:  K O Cox; S J Hardy
Journal:  Immunology       Date:  1985-06       Impact factor: 7.397

  2 in total

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