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Literature DB >> 6172537

T cell clones with dual specificity for M1s and various major histocompatibility complex determinants.

S R Webb, K Molnar-Kimber, J Bruce, J Sprent, D B Wilson.

Abstract

A high proportion of T cell clones derived from bulk cultures selected to M1s a,d determinants were found to have joint specificity for allo-H-2 determinants, and vice versa. Significantly, the patterns of H-2 alloreactivity shown by clones selected to M1sa,b determinants appeared to be random. The possible implications of these findings are discussed.

Entities: Gene

Mesh：

Substances：
Epitopes
H-2 Antigens

Year: 1981 PMID： 6172537 PMCID： PMC2186545 DOI： 10.1084/jem.154.6.1970

Source DB: PubMed Journal: J Exp Med ISSN： 0022-1007 Impact factor: 14.307

12 in total

1. Cross-reactivity exists between Mlsa and Mlsd lymphocyte-activating determinants as demonstrated by the negative clonal selection of responder cells in a mixed lymphocyte reaction.

Authors: J J Ryan; A Ahmed; P Kind; K W Sell
Journal: Transplant Proc Date: 1979-06 Impact factor: 1.066

2. Influence of M-locus (non-H-2) and K-end and D-end (H-2-region) incompatibility on heart muscle allograft survival time.

Authors: B Huber; P Démant; H Festenstein
Journal: Transplant Proc Date: 1973-12 Impact factor: 1.066

3. Genetic studies and effect on skin allograft survival of DBA-2 DAG, Ly, and M-locus antigens.

Authors: J A Sachs; B Huber; J Peña-Martinez; H Festenstein
Journal: Transplant Proc Date: 1973-12 Impact factor: 1.066

4. The H-2D and H-2K regions of the major histocompatibility system and the M locus of the mouse investigated by parabiosis.

Authors: N W Nisbet; J Edwards
Journal: Transplant Proc Date: 1973-12 Impact factor: 1.066

Review 5. Immunogenetic and biological aspects of in vitro lymphocyte allotransformation (MLR) in the mouse.

Authors: H Festenstein
Journal: Transplant Rev Date: 1973

6. Evidence that strong Mls determinants are nonpolymorphic.

Authors: K L Molnar-Kimber; J Sprent
Journal: Transplantation Date: 1981-05 Impact factor: 4.939

7. Genetic linkage between Lym-1, Sas-1 and Mls loci.

Authors: H B Dickler; D L Rosenstreich; A Ahmed; D H Sachs
Journal: Immunogenetics Date: 1980 Impact factor: 2.846

8. Mouse cell-mediated lympholysis assay in serum-free and mouse serum-supplemented media: culture conditions and genetic factors.

Authors: A B Peck; F H Bach
Journal: Scand J Immunol Date: 1975 Impact factor: 3.487

9. Absence of H-2 restriction in primary and secondary mixed-lymphocyte reactions to strong M1s determinants.

Authors: K Molnar-Kimber; J Sprent
Journal: J Exp Med Date: 1980-02-01 Impact factor: 14.307

10. Lethal graft-versus-host disease after bone marrow transplantation across minor histocompatibility barriers in mice. Prevention by removing mature T cells from marrow.

Authors: R Korngold; J Sprent
Journal: J Exp Med Date: 1978-12-01 Impact factor: 14.307

16 in total

Review 1. Superantigens: biology, immunology, and potential role in disease.

Authors: C G Drake; B L Kotzin
Journal: J Clin Immunol Date: 1992-05 Impact factor: 8.317

2. Multi-gene/allele control of Mlsb of CBA/H.

Authors: R E Click; A Adelmann
Journal: Immunogenetics Date: 1989 Impact factor: 2.846

3. Differential induction of interferon gamma gene expression after activation of CD4+ T cells by conventional antigen and Mls superantigen.

Authors: R Patarca; F Y Wei; M V Iregui; H Cantor
Journal: Proc Natl Acad Sci U S A Date: 1991-04-01 Impact factor: 11.205

4. Multigene control of Mlsc.

Authors: R E Click; A Adelmann
Journal: Immunogenetics Date: 1988 Impact factor: 2.846

Review 5. Recognition of multiple class II signals by murine T cell antigen receptors. Speculation regarding the relationships among autoreactive, antigen-specific and alloreactive T cells.

Authors: B W Needleman
Journal: Immunol Res Date: 1988 Impact factor: 2.829

6. Immune responses in vitro, XIV. Undetectability of Mlsb- and Mlsc-encoded products on F1 cells possessing Mlsa or Mlsd.

Authors: R E Click; D Schneider; L A Sitzmann; M M Azar
Journal: Immunogenetics Date: 1984 Impact factor: 2.846

7. Interactions between MHC-encoded products and cloned T-cells. I. Fine specificity of induction of proliferation and lysis.

Authors: F Albert; M Buferne; C Boyer; A M Schmitt-Verhulst
Journal: Immunogenetics Date: 1982 Impact factor: 2.846