Literature DB >> 6172071

Pathomechanisms in cell metabolism: a key to treatment of Bell's palsy.

E Stennert.   

Abstract

In light of current research the classic theory on the vicious circle of Bell's palsy has to be reconsidered. New findings through electron microscopy and biochemistry concerning the structure and metabolism of cells have presented aspects which have consequences for treatment of the disease. These aspects deal mainly with the pathomechanisms of cell metabolism whose interactions also cause a vicious circle, leading to a breakdown of microcirculation and ultimately to the death of the cells due to hypoxia and acidosis. It is therefore suggested that the aim of an effective therapy must be the early normalization of cell metabolism by improving microcirculation. A fitting treatment protocol is presented and the extraordinarily good results are discussed.

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Year:  1981        PMID: 6172071     DOI: 10.1177/000348948109000613

Source DB:  PubMed          Journal:  Ann Otol Rhinol Laryngol        ISSN: 0003-4894            Impact factor:   1.547


  5 in total

1.  The clinical problem of Bell's palsy: is treatment with steroids effective?

Authors:  I G Williamson; T R Whelan
Journal:  Br J Gen Pract       Date:  1996-12       Impact factor: 5.386

2.  Susceptibility of isolated rat facial nerve to anaerobic stress.

Authors:  R Jund; E Kastenbauer
Journal:  Eur Arch Otorhinolaryngol       Date:  1997       Impact factor: 2.503

3.  Conservative treatment of Bell's palsy with steroids and dextran-pentoxiphylline combined therapy.

Authors:  M Kinishi; M Amatsu; H Hosomi
Journal:  Eur Arch Otorhinolaryngol       Date:  1991       Impact factor: 2.503

4.  Modified Stennert's Protocol in Treating Acute Peripheral Facial Nerve Paralysis: Our Experience.

Authors:  S G Mahesh; D R Nayak; R Balakrishnan; P Pavithran; S Pillai; Abhishek Sharma
Journal:  Indian J Otolaryngol Head Neck Surg       Date:  2012-01-06

Review 5.  Pentoxifylline. A review of its pharmacodynamic and pharmacokinetic properties, and its therapeutic efficacy.

Authors:  A Ward; S P Clissold
Journal:  Drugs       Date:  1987-07       Impact factor: 9.546

  5 in total

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