| Literature DB >> 6170301 |
P J Johnson, W M Melia, M K Palmer, B Portmann, R Williams.
Abstract
An analysis of survival time of 57 West European patients with hepatocellular carcinoma was carried out to define which of several possible factors (age, sex, cirrhosis and raised serum alpha-foetoprotein (AFP)) influenced survival. Although survival was significantly longer in younger patients (P less than 0.02) and in patients with normal serum AFP (P less than 0.01), multivariate analysis showed that significant variation in survival time is better explained by the single factor, the presence of cirrhosis, than by AFP level. This does not seem to apply for patients with this tumour in Africa and the Far East, and there may be a fundamental difference in the natural history of the tumour between high- and low-incidence areas.Entities:
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Year: 1981 PMID： 6170301 PMCID： PMC2010797 DOI： 10.1038/bjc.1981.218
Source DB: PubMed Journal: Br J Cancer ISSN： 0007-0920 Impact factor: 7.640