Literature DB >> 6170110

Complete nucleotide sequence and organization of the Moloney murine sarcoma virus genome.

E P Reddy, M J Smith, S A Aaronson.   

Abstract

The complete nucleotide sequence of a mammalian transforming retrovirus. Moloney murine sarcoma virus, has been determined. MSV, recombinant virus derived of helper viral and cellular sequences, possesses termini resembling prokaryotic transposable elements. The viral genome has the coding capacity for the Moloney murine leukemia virus gag gene product and contains large deletions in pol and env genes. A large open reading frame encompassing its cell-derived sequences codes for its putative transforming protein. The nature of some of the important domains in the viral genome has been established, and their structure is discussed in relation to their function.

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Year:  1981        PMID： 6170110     DOI： 10.1126/science.6170110

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  47 in total

1.  Nucleotide sequence analysis of the BALB/c murine sarcoma virus transforming gene.

Authors:  E P Reddy; D Lipman; P R Andersen; S R Tronick; S A Aaronson
Journal:  J Virol       Date:  1985-03       Impact factor: 5.103

2.  Interferon alters the pattern of secreted proteins from Ehrlich ascites-tumour cells.

Authors:  S Tominaga; K Tominaga
Journal:  Biochem J       Date:  1989-07-01       Impact factor: 3.857

3.  A recessive cellular mutation in v-fes-transformed mink cells restores contact inhibition and anchorage-dependent growth.

Authors:  J R Haynes; J R Downing
Journal:  Mol Cell Biol       Date:  1988-06       Impact factor: 4.272

4.  The retrovirus pol gene encodes a product required for DNA integration: identification of a retrovirus int locus.

Authors:  A T Panganiban; H M Temin
Journal:  Proc Natl Acad Sci U S A       Date:  1984-12       Impact factor: 11.205

5.  Envelope gene sequences which encode the gp52 protein of spleen focus-forming virus are required for the induction of erythroid cell proliferation.

Authors:  D L Linemeyer; J G Menke; S K Ruscetti; L H Evans; E M Scolnick
Journal:  J Virol       Date:  1982-07       Impact factor: 5.103

6.  Oncogene amplification in breast cancer.

Authors:  M Donovan-Peluso; A M Contento; H Tobon; B Ripepi; J Locker
Journal:  Am J Pathol       Date:  1991-04       Impact factor: 4.307

7.  Molecular cloning and characterization of a leukemia-inducing myeloproliferative sarcoma virus and two of its temperature-sensitive mutants.

Authors:  R Kollek; C Stocking; F Smadja-Joffe; W Ostertag
Journal:  J Virol       Date:  1984-06       Impact factor: 5.103

8.  Nucleotide sequence of the simian sarcoma virus genome: demonstration that its acquired cellular sequences encode the transforming gene product p28sis.

Authors:  S G Devare; E P Reddy; J D Law; K C Robbins; S A Aaronson
Journal:  Proc Natl Acad Sci U S A       Date:  1983-02       Impact factor: 11.205

9.  Nucleotide sequences of feline sarcoma virus long terminal repeats and 5' leaders show extensive homology to those of other mammalian retroviruses.

Authors:  A Hampe; M Gobet; J Even; C J Sherr; F Galibert
Journal:  J Virol       Date:  1983-01       Impact factor: 5.103

10.  Molecular cloning and chromosomal mapping of a human locus related to the transforming gene of Moloney murine sarcoma virus.

Authors:  K Prakash; O W McBride; D C Swan; S G Devare; S R Tronick; S A Aaronson
Journal:  Proc Natl Acad Sci U S A       Date:  1982-09       Impact factor: 11.205
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