Literature DB >> 6169791

Assay of defective-interfering semliki forest virus by the inhibition of synthesis of virus-specified RNAs.

A D Barrett, C F Crouch, N J Dimmock.   

Abstract

We describe a simple, rapid and reproducible assay for defective-interfering Semliki Forest virus (DI SFV) which is based on the inhibition of synthesis of virus-specified RNAs in SFV-infected cells. Using the assay, we have been able to show that DI virus is generated by a single passage in baby hamster kidney (BHK) cells in an inoculum which contained no detectable DI virus and we have calculated the u.v. target size of the interfering activity.

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Year:  1981        PMID: 6169791     DOI: 10.1099/0022-1317-54-2-273

Source DB:  PubMed          Journal:  J Gen Virol        ISSN: 0022-1317            Impact factor:   3.891


  4 in total

1.  Properties of lymphocytic choriomeningitis virus interfering particles.

Authors:  L Martínez Peralta; F Lehmann-Grube
Journal:  Arch Virol       Date:  1983       Impact factor: 2.574

2.  Defective interfering influenza virus inhibits immunopathological effects of infectious virus in the mouse.

Authors:  D J Morgan; N J Dimmock
Journal:  J Virol       Date:  1992-02       Impact factor: 5.103

3.  Properties of host and virus which influence defective interfering virus mediated-protection of mice against Semliki Forest virus lethal encephalitis. Brief report.

Authors:  A D Barrett; N J Dimmock
Journal:  Arch Virol       Date:  1984       Impact factor: 2.574

4.  Analysis of extracellular West Nile virus particles produced by cell cultures from genetically resistant and susceptible mice indicates enhanced amplification of defective interfering particles by resistant cultures.

Authors:  M A Brinton
Journal:  J Virol       Date:  1983-06       Impact factor: 5.103

  4 in total

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