| Literature DB >> 6169365 |
Abstract
We have synthesized a new medium, sulfhydrylcellulose, for affinity chromatography of mercurated polynucleotides. It is the product of reaction between aminoethylcellulose and N-acetylhomocysteine thiolactone. Sulfhydrylcellulose carries up to 90 mumol of SH groups/g and is inexpensive, easy to prepare, and stable. Because it binds mercurated RNA specifically and reversibly and exhibits no size discrimination, sulfhydrylcellulose should have wide applications.Entities:
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Year: 1981 PMID： 6169365 DOI： 10.1021/bi00518a001
Source DB: PubMed Journal: Biochemistry ISSN： 0006-2960 Impact factor: 3.162