Literature DB >> 6169306

Sodium polyanethol sulfonate inactivation of aminoglycosides.

D J Krogstad, P R Murray, G G Granich, A C Niles, J H Ladenson, J E Davis.   

Abstract

Sodium polyanethol sulfonate and another polyanion (dextran sulfate) both inhibited aminoglycoside activity in vitro. This effect was not produced by an otherwise similar neutral carbohydrate (dextran) or by neutral detergents (Brij-35, Triton X-100) but was antagonized by an anion-exchange resin (Dowex 1X8-50). We conclude that the inactivation of aminoglycosides by sodium polyanethol sulfonate results from its polyanionic nature and is unrelated to its detergent properties.

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Year:  1981        PMID： 6169306      PMCID： PMC181680          DOI： 10.1128/AAC.20.2.272

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  9 in total

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Journal:  J Infect Dis       Date:  1971-12       Impact factor: 5.226

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Authors:  M E Belding; S J Klebanoff
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  9 in total
  8 in total

1.  Effectiveness of resins in neutralizing antibiotic activities in bactec plus Aerobic/F culture medium.

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Journal:  J Clin Microbiol       Date:  1998-12       Impact factor: 5.948

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Authors:  John F Regan; Manohar R Furtado; Maxim G Brevnov; Jeanne A Jordan
Journal:  J Mol Diagn       Date:  2012-01-11       Impact factor: 5.568

Review 3.  Current controversies in the detection of septicemia.

Authors:  G Pierce; P R Murray
Journal:  Eur J Clin Microbiol       Date:  1986-10       Impact factor: 3.267

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Authors:  P R Murray; A C Niles
Journal:  J Clin Microbiol       Date:  1982-11       Impact factor: 5.948

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Authors:  J E Tisdale; M T Pasko; J M Mylotte
Journal:  Antimicrob Agents Chemother       Date:  1989-09       Impact factor: 5.191

8.  Inactivation of the polyanionic detergent sodium polyanetholsulfonate by hemoglobin.

Authors:  S C Edberg; M K Edberg
Journal:  J Clin Microbiol       Date:  1983-11       Impact factor: 5.948
  8 in total

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