Literature DB >> 6169090

Isoelectric focusing of human hemoglobins.

Y Beuzard, F Galacteros, F Braconnier, A Dubart, J Chen-Marotel, J Caburi-Martin, N Monplaisir, M Sellaye, C Saint Martin, S Seytor, P Basset, J Rosa.   

Abstract

Isoelectric focusing on thin layer of acrylamide gel has been used for the characterization of 79 different variants of hemoglobin A. This method has replaced the cellulose acetate electrophoresis in clinical laboratories in Martinique, Guadeloupe and Creteil for the detection of abnormal hemoglobins in populations at risk. Up to now 15,000 samples from adults have been evaluated. In addition this method has been used for the screening of 7,000 cord blood samples and for the prenatal diagnosis of severe hemoglobinopathies.

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Year:  1981        PMID: 6169090

Source DB:  PubMed          Journal:  Prog Clin Biol Res        ISSN: 0361-7742


  1 in total

1.  Hemoglobin abnormalities. An evaluation on new-born infants and their mothers in a maternity unit close to Brazzaville (P.R. Congo).

Authors:  M Lallemant; F Galacteros; S Lallemant-Lecoeur; J Feingold; P Carnevale; V Boukila; J Mouchet; J Rosa
Journal:  Hum Genet       Date:  1986-09       Impact factor: 4.132

  1 in total

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