Literature DB >> 6168772

Monoclonal antibodies to the influenza A virus nucleoprotein affecting RNA transcription.

K L van Wyke, W J Bean, R G Webster.   

Abstract

Monoclonal antibodies were used to map the antigenic domains of the A/WSN/33 (HoN1) influenza virus nucleoprotein. Three nonoverlapping antigenic regions of the nucleoprotein were identified by using competitive-binding enzyme-linked immunosorbent assays. Monoclonal antibodies to two nucleoprotein domains inhibited in vitro transcription of viral RNA, suggesting that these specific regions of the nucleoprotein are topographically or functionally involved in RNA transcription.

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Year:  1981        PMID: 6168772      PMCID: PMC171292          DOI: 10.1128/JVI.39.1.313-317.1981

Source DB:  PubMed          Journal:  J Virol        ISSN: 0022-538X            Impact factor:   5.103


  19 in total

1.  Protein measurement with the Folin phenol reagent.

Authors:  O H LOWRY; N J ROSEBROUGH; A L FARR; R J RANDALL
Journal:  J Biol Chem       Date:  1951-11       Impact factor: 5.157

2.  Inhibition of transcription by immunoglobulins directed against the ribonucleoprotein of homotypic and heterotypic vesicular stomatitis viruses.

Authors:  A R Carroll; R R Wagner
Journal:  J Virol       Date:  1978-02       Impact factor: 5.103

3.  Isolation of pure IgG1, IgG2a and IgG2b immunoglobulins from mouse serum using protein A-sepharose.

Authors:  P L Ey; S J Prowse; C R Jenkin
Journal:  Immunochemistry       Date:  1978-07

4.  Characterization of the ribonucleoprotein and neuraminidase of influenza A viruses by immunodiffusion.

Authors:  G C Schild; H G Pereira
Journal:  J Gen Virol       Date:  1969-04       Impact factor: 3.891

5.  Evidence for antigenic variation in influenza A nucleoprotein.

Authors:  G C Schild; J S Oxford; R W Newman
Journal:  Virology       Date:  1979-03       Impact factor: 3.616

6.  Influenza virion transcriptase: synthesis in vitro of large, polyadenylic acid-containing complementary RNA.

Authors:  S J Plotch; R M Krug
Journal:  J Virol       Date:  1977-01       Impact factor: 5.103

7.  Gene composition of high-yielding influenza vaccine strains obtained by recombination.

Authors:  M Baez; P Palese; E D Kilbourne
Journal:  J Infect Dis       Date:  1980-03       Impact factor: 5.226

8.  Antigenic variation of influenza A virus nucleoprotein detected with monoclonal antibodies.

Authors:  K L van Wyke; V S Hinshaw; W J Bean; R G Webster
Journal:  J Virol       Date:  1980-07       Impact factor: 5.103

9.  Antiviral activity of antiserum specific for an influenza virus neuraminidase.

Authors:  E D Kilbourne; W G Laver; J L Schulman; R G Webster
Journal:  J Virol       Date:  1968-04       Impact factor: 5.103

10.  Identification of the defective genes in three mutant groups of influenza virus.

Authors:  M B Ritchey; P Palese
Journal:  J Virol       Date:  1977-03       Impact factor: 5.103

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  23 in total

1.  The role of cell surface expression of influenza virus neuraminidase in induction of human lymphocyte apoptosis.

Authors:  Joan E Nichols; Jean A Niles; Elisa H Fleming; Norbert J Roberts
Journal:  Virology       Date:  2019-06-10       Impact factor: 3.616

2.  Location of antigenic sites recognized by monoclonal antibodies in the influenza A virus nucleoprotein molecule.

Authors:  Natalia L Varich; Konstantin S Kochergin-Nikitsky; Evgeny V Usachev; Olga V Usacheva; Alexei G Prilipov; Robert G Webster; Nikolai V Kaverin
Journal:  J Gen Virol       Date:  2009-03-18       Impact factor: 3.891

3.  Transport of incoming influenza virus nucleocapsids into the nucleus.

Authors:  K Martin; A Helenius
Journal:  J Virol       Date:  1991-01       Impact factor: 5.103

Review 4.  Recognition of influenza virus proteins by cytotoxic T lymphocytes.

Authors:  A R Townsend
Journal:  Immunol Res       Date:  1987       Impact factor: 2.829

5.  Transcription antitermination during influenza viral template RNA synthesis requires the nucleocapsid protein and the absence of a 5' capped end.

Authors:  A R Beaton; R M Krug
Journal:  Proc Natl Acad Sci U S A       Date:  1986-09       Impact factor: 11.205

6.  Apoptosis: a mechanism of cell killing by influenza A and B viruses.

Authors:  V S Hinshaw; C W Olsen; N Dybdahl-Sissoko; D Evans
Journal:  J Virol       Date:  1994-06       Impact factor: 5.103

7.  Serine 3 is critical for phosphorylation at the N-terminal end of the nucleoprotein of influenza virus A/Victoria/3/75.

Authors:  M Arrese; A Portela
Journal:  J Virol       Date:  1996-06       Impact factor: 5.103

8.  Use of monoclonal antibodies for rapid detection of influenza A virus in nasopharyngeal secretions.

Authors:  P Pothier; G A Denoyel; S Ghim; G Prudhomme de Saint Maur; F Freymuth
Journal:  Eur J Clin Microbiol       Date:  1986-06       Impact factor: 3.267

9.  Mutational analysis of influenza A virus nucleoprotein: identification of mutations that affect RNA replication.

Authors:  I Mena; E Jambrina; C Albo; B Perales; J Ortín; M Arrese; D Vallejo; A Portela
Journal:  J Virol       Date:  1999-02       Impact factor: 5.103

10.  Human Alveolar Macrophages May Not Be Susceptible to Direct Infection by a Human Influenza Virus.

Authors:  David B Ettensohn; Mark W Frampton; Joan E Nichols; Norbert J Roberts
Journal:  J Infect Dis       Date:  2016-09-06       Impact factor: 5.226

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