| Literature DB >> 6168772 |
K L van Wyke, W J Bean, R G Webster.
Abstract
Monoclonal antibodies were used to map the antigenic domains of the A/WSN/33 (HoN1) influenza virus nucleoprotein. Three nonoverlapping antigenic regions of the nucleoprotein were identified by using competitive-binding enzyme-linked immunosorbent assays. Monoclonal antibodies to two nucleoprotein domains inhibited in vitro transcription of viral RNA, suggesting that these specific regions of the nucleoprotein are topographically or functionally involved in RNA transcription.Entities:
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Year: 1981 PMID: 6168772 PMCID: PMC171292 DOI: 10.1128/JVI.39.1.313-317.1981
Source DB: PubMed Journal: J Virol ISSN: 0022-538X Impact factor: 5.103