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Literature DB >> 616864

Once daily sotalol in the treatment of hypertension.

Abstract

In a small group of hypertensive patients studied at home, once daily early morning sotalol therapy effectively decreased lying, standing, and post-exercise blood pressure and pulse rate. A dose-response relationship was seen. Adverse effects were mild and transient. The once daily regimen is easy to administer and appears to give precision in blood pressure reduction. Providing there is no subsequent escape from control, once daily beta-blocking therapy should aid long-term hypertension treatment in general practice.

Entities: Chemical Disease Species

Mesh：

Substances：
Sotalol

Year: 1977 PMID： 616864 PMCID： PMC2158659

Source DB: PubMed Journal: J R Coll Gen Pract ISSN： 0035-8797

12 in total

Once daily sotalol in the treatment of hypertension.

1. Diseases of the cardiovascular system. Hypertension--I.

2. Untoward effects associated with practolol administration: oculomucocutaneous syndrome.

3. Pharmacological and toxicological properties of two new beta-adrenergic receptor antagonists.

4. Cutaneous and ocular reactions to practolol.

5. Drug therapy: patient compliance.

6. To be taken as directed.

7. Sclerosing peritonitis, an unusual reaction to a beta-adrenergic-blocking drug (practolol).

8. Drug therapy of hypertension: what we have, what we need, what we expect.

Review 9. Beta-adrenergic receptor blocking drugs in hypertension.

10. A study of once daily tenormin (atenolol) in hypertension: some implications in patient compliance.

1. Fixed combination of sotalol and hydrochlorothiazide in the treatment of uncomplicated hypertension.

2. Pharmacokinetics of sotalol after chronic administration to patients with renal insufficiency.