Literature DB >> 6168491

Trypsin-induced activation of the thiol esters in alpha 2-macroglobulin generates a short-lived intermediate ('nascent' alpha 2-M) that can react rapidly to incorporate not only methylamine or putrescine but also proteins lacking proteinase activity.

L Sottrup-Jensen, T E Petersen, S Magnusson.   

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Year:  1981        PMID： 6168491     DOI： 10.1016/0014-5793(81)81096-4

Source DB:  PubMed          Journal:  FEBS Lett        ISSN： 0014-5793            Impact factor:   4.124


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  15 in total

1.  Limulus alpha 2-macroglobulin. First evidence in an invertebrate for a protein containing an internal thiol ester bond.

Authors:  P B Armstrong; J P Quigley
Journal:  Biochem J       Date:  1987-12-15       Impact factor: 3.857

2.  The conformational changes of alpha 2-macroglobulin induced by methylamine or trypsin. Characterization by extrinsic and intrinsic spectroscopic probes.

Authors:  L J Larsson; P Lindahl; C Hallén-Sandgren; I Björk
Journal:  Biochem J       Date:  1987-04-01       Impact factor: 3.857

3.  Interaction and complex-formation between the eosinophil cationic protein and alpha 2-macroglobulin.

Authors:  C G Peterson; P Venge
Journal:  Biochem J       Date:  1987-08-01       Impact factor: 3.857

4.  Alpha 2-macroglobulin used to isolate intracellular endopeptidases from mammalian cells in culture.

Authors:  L A Slot; K B Hendil
Journal:  Biochem J       Date:  1988-10-15       Impact factor: 3.857

5.  Differential scanning calorimetry of alpha 2-macroglobulin and alpha 2-macroglobulin-proteinase complexes.

Authors:  J F Chlebowski; K Williams
Journal:  Biochem J       Date:  1983-03-01       Impact factor: 3.857

6.  Stoichiometry of reactions of alpha 2-macroglobulin with trypsin and chymotrypsin.

Authors:  I Björk; L J Larsson; T Lindblom; E Raub
Journal:  Biochem J       Date:  1984-01-01       Impact factor: 3.857

7.  Probing the stability of native and activated forms of alpha2-macroglobulin.

Authors:  Steven J Kaczowka; Lara S Madding; Kevin L Epting; Robert M Kelly; George J Cianciolo; Salvatore V Pizzo
Journal:  Int J Biol Macromol       Date:  2007-10-07       Impact factor: 6.953

8.  Binding of proteinases to human alpha 2-macroglobulin with its thioester bonds cleaved by methylamine in the presence of a thiol-group-cyanylating reagent.

Authors:  I Björk
Journal:  Biochem J       Date:  1985-10-15       Impact factor: 3.857

9.  Antigen delivery by alpha(2)-macroglobulin enhances the cytotoxic T lymphocyte response.

Authors:  Edith V Bowers; Jeffrey J Horvath; Jennifer E Bond; George J Cianciolo; Salvatore V Pizzo
Journal:  J Leukoc Biol       Date:  2009-08-03       Impact factor: 4.962

10.  Evidence for similar conformational changes in alpha 2-macroglobulin on reaction with primary amines or proteolytic enzymes.

Authors:  I Björk; W W Fish
Journal:  Biochem J       Date:  1982-11-01       Impact factor: 3.857
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