Literature DB >> 6167911

Substance P immunoreactive sensory nerves supply the rat iris and cornea.

A Miller, M Costa, J B Furness, I W Chubb.   

Abstract

The presence, distribution and origin of substance P immunoreactive axons in the rat iris and cornea were investigated in whole mount preparations. A dense network of substance P immunoreactive axons was found throughout the iris but not in the ciliary body. In the cornea, substance P immunoreactive axons were found in the substantia propria, in the subepithelial layer and in the corneal epithelium. Following electrocoagulation of the ophthalmic nerve, most of the substance P immunoreactive axons in the iris and cornea disappeared. No changes in the substance P immunoreactive axons occurred after removal of the superior cervical ganglion. It is concluded that the iris and the cornea are supplied by sensory nerves containing substance P immunoreactivity.

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Year:  1981        PMID: 6167911     DOI: 10.1016/0304-3940(81)90005-7

Source DB:  PubMed          Journal:  Neurosci Lett        ISSN: 0304-3940            Impact factor:   3.046


  28 in total

1.  Synergistic effect with Phe-Gly-Leu-Met-NH2 of the C-terminal of substance P and insulin-like growth factor-1 on epithelial wound healing of rabbit cornea.

Authors:  M Nakamura; T Chikama; T Nishida
Journal:  Br J Pharmacol       Date:  1999-05       Impact factor: 8.739

2.  Innervation of the uvea by galanin and somatostatin immunoreactive axons in macaques and baboons.

Authors:  Sally I Firth; Paul L Kaufman; Baptiste J De Jean; John M Byers; David W Marshak
Journal:  Exp Eye Res       Date:  2002-07       Impact factor: 3.467

3.  A new role of substance P as an injury-inducible messenger for mobilization of CD29(+) stromal-like cells.

Authors:  Hyun Sook Hong; Jungsun Lee; EunAh Lee; Young Sam Kwon; Eunkyung Lee; Woosung Ahn; Mei Hua Jiang; Jae Chan Kim; Youngsook Son
Journal:  Nat Med       Date:  2009-03-08       Impact factor: 53.440

4.  Target-specific innervation by autonomic and sensory nerve fibers in hairy fetal skin transplanted into the anterior eye chamber of adult rat.

Authors:  N Katoh; S Ueda; Y Matsumoto; S Kishimoto; H Yasuno; M Kawata
Journal:  Cell Tissue Res       Date:  1991-11       Impact factor: 5.249

5.  Immunohistochemical demonstration of neurotensin and tyrosine hydroxylase in iris nerves of the rabbit eye.

Authors:  D E Hernandez; L Jennes
Journal:  Histochemistry       Date:  1989

6.  The role of sensory fibres in the rat splanchnic nerve in the regulation of adrenal medullary secretion during stress.

Authors:  Z Khalil; B G Livett; P D Marley
Journal:  J Physiol       Date:  1986-01       Impact factor: 5.182

7.  Galanin-immunoreactive nerves in the rat iris: alterations induced by denervations.

Authors:  I Strömberg; H Björklund; T Melander; A Rökaeus; T Hökfelt; L Olson
Journal:  Cell Tissue Res       Date:  1987-11       Impact factor: 5.249

Review 8.  Autonomic control of the eye.

Authors:  David H McDougal; Paul D Gamlin
Journal:  Compr Physiol       Date:  2015-01       Impact factor: 9.090

Review 9.  Regulatory peptides in the eye.

Authors:  R A Stone; Y Kuwayama; A M Laties
Journal:  Experientia       Date:  1987-07-15

10.  On the origin and distribution of vasoactive intestinal polypeptide-, peptide HI-, and cholecystokinin-like-immunoreactive nerve fibers in the rat iris.

Authors:  H Björklund; J Fahrenkrug; A Seiger; J J Vanderhaeghen; L Olson
Journal:  Cell Tissue Res       Date:  1985       Impact factor: 5.249

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