Literature DB >> 6166497

Antidiuretic activities of substance P and its analogs.

M Ukai, T Nagase, M Hirohashi, N Yanaihara.   

Abstract

Substance P (SP) and analogs, including 5 nucleoside (ARA or HRA)-peptides, were examined for antidiuretic activity in ethanolized rats. The activity was potent in the analogs embodying the C-terminal hexapeptide, weak in the nucleoside-pentapeptide, and negligible in the nucleoside-tetrapeptide. In addition, the activity was increased by acylation of the hexapeptide. The antidiuretic potencies were also compared with the hypotensive potencies.

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Year:  1981        PMID： 6166497     DOI： 10.1007/BF01986174

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  19 in total

1.  THE RELATIONSHIP OF ANTIDIURETIC HORMONE SECRETION TO SURGICAL STRESS.

Authors:  W H MORAN; W A SHUAYB; B ZIMMERMANN
Journal:  Surgery       Date:  1964-07       Impact factor: 3.982

2.  An unidentified depressor substance in certain tissue extracts.

Authors:  U S V Euler; J H Gaddum
Journal:  J Physiol       Date:  1931-06-06       Impact factor: 5.182

3.  Depressor substances in extracts of intestine.

Authors:  J H Gaddum; H Schild
Journal:  J Physiol       Date:  1934-12-14       Impact factor: 5.182

4.  Effects of natural analogues of substance P on the motility of human gastrointestinal tract in vitro.

Authors:  L Zappia; E Molina; M Sianesi; G Bertaccini
Journal:  J Pharm Pharmacol       Date:  1978-09       Impact factor: 3.765

5.  Substance P and analgesia.

Authors:  J M Stewart; C J Getto; K Neldner; E B Reeve; W A Krivoy; E Zimmermann
Journal:  Nature       Date:  1976-08-26       Impact factor: 49.962

6.  Identification of the motoneuron-depolarizing peptide in bovine dorsal root as hypothalamic substance P.

Authors:  T Takahashi; S Konishi; D Powell; S E Leeman; M Otsuka
Journal:  Brain Res       Date:  1974-06-14       Impact factor: 3.252

7.  Isolation of a sialogogic peptide from bovine hypothalamic tissue and its characterization as substance P.

Authors:  M M Chang; S E Leeman
Journal:  J Biol Chem       Date:  1970-09-25       Impact factor: 5.157

8.  In vitro activities of some synthetic substance P analogs.

Authors:  R E Chipkin; J M Stewart; V E Sweeney; K Harris; R Williams
Journal:  Arch Int Pharmacodyn Ther       Date:  1979-08

9.  Effects of neurotensin and substance P on plasma insulin, glucagon and glucose levels.

Authors:  M Brown; W Vale
Journal:  Endocrinology       Date:  1976-03       Impact factor: 4.736

10.  Biological activity of C-terminal partial sequences of substance P.

Authors:  R W Bury; M L Mashford
Journal:  J Med Chem       Date:  1976-06       Impact factor: 7.446
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  2 in total

1.  Axons containing neuropeptide Y innervate arginine vasopressin-containing neurons in the rat paraventricular nucleus. Dual electron microscopic immunolabeling.

Authors:  Y Kagotani; Y Tsuruo; S Hisano; S Daikoku; K Chihara
Journal:  Histochemistry       Date:  1989

2.  Synaptic regulation of paraventricular arginine vasopressin-containing neurons by neuropeptide Y-containing monoaminergic neurons in rats. Electron-microscopic triple labeling.

Authors:  Y Kagotani; Y Tsuruo; S Hisano; S Daikoku; K Chihara
Journal:  Cell Tissue Res       Date:  1989-08       Impact factor: 5.249
  2 in total

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