| Literature DB >> 6166365 |
F M Hallinan, S H Lee, K R Rozee.
Abstract
The effect of the ribonuclease inhibitor polyvinyl sulfate on the activity of retroviral DNA polymerase and terminal c transferase was examined. This substance was found to be a potent inhibitor of these enzymes by virtue of competition between the sulfated sidechains of the molecule and the template primer for a site on the enzyme. The significance of these findings in relation to searching for reverse transcriptase is discussed.Entities:
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Year: 1981 PMID： 6166365
Source DB: PubMed Journal: Cancer Biochem Biophys ISSN： 0305-7232