| Literature DB >> 6165216 |
S C Wong, M A Ali, S E Boyadjian.
Abstract
A trimodal distribution of the amounts of Hb S in 56 sickle cell heterozygotes was observed. The variable amounts of Hb S were directly related to the mean cell volume and the mean cell Hb and were a result of the difference in net synthesis of Hb S due to the presence of the alpha-thalassaemia. Double heterozygotes for the Hb S and alpha-thalassaemia-1 genes, besides having a lower amount of Hb S in the red blood cells, were found to have lower Hb and slightly elevated Hb A2 levels.Mesh：
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Year: 1981 PMID： 6165216 DOI： 10.1159/000207172
Source DB: PubMed Journal: Acta Haematol ISSN： 0001-5792 Impact factor: 2.195