Literature DB >> 6163737

Interferon immunoregulation of antibody response in normal and autoimmune mice is mediated by suppressor T cell subsets.

A M Attallah, A Urritia-Shaw, R Y Khalit, A D Steinberg, A Ahmed.   

Abstract

The mechanism through which interferon exerts immunoregulatory influence on antibody production in autoimmune NZB mice and normal Balb/C mice was studied. Interferon suppressed T cell-dependent anti-SRBC response in normal mice indirectly by activating suppressor T cells. The suppressor cell activity by interferon is mediated by Ly123+ cells presumably acting as feedback regulators for the suppression.

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Year:  1981        PMID: 6163737     DOI: 10.1159/000232714

Source DB:  PubMed          Journal:  Int Arch Allergy Appl Immunol        ISSN: 0020-5915


  2 in total

1.  Equal distribution of T-lymphocyte subpopulations in thymus and spleen cells of NZB and BALB/c mice.

Authors:  J Müller-Quernheim; U Botzenhardt; D von Steldern
Journal:  Rheumatol Int       Date:  1984       Impact factor: 2.631

2.  Interferon and natural killer cells in systemic lupus erythematosus.

Authors:  O Strannegård; S Hermodsson; G Westberg
Journal:  Clin Exp Immunol       Date:  1982-11       Impact factor: 4.330

  2 in total

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