Literature DB >> 6162839

Inhibition of deoxyribonucleic acid replication in Bacillus brevis by ribonucleic acid polymerase inhibitors.

S Bhattacharya, N Sarkar.   

Abstract

The incorporation of [3H]thymidine into deoxyribonucleic acid by exponentially growing cells of Bacillus brevis was inhibited by streptolydigin and rifampin in the same concentration range in which these drugs inhibit ribonucleic acid synthesis. Complete inhibition occurred within one-third generation time after drug addition, suggesting an effect on deoxyribonucleic acid chain elongation.

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Year:  1981        PMID: 6162839      PMCID: PMC217154          DOI: 10.1128/jb.145.3.1442-1444.1981

Source DB:  PubMed          Journal:  J Bacteriol        ISSN: 0021-9193            Impact factor:   3.490


  13 in total

1.  Involvement of RNA polymerase in the synthesis of DNA by growing and toluene-treated cells of Bacillus brevis.

Authors:  N Sarkar
Journal:  Biochem Biophys Res Commun       Date:  1975-01-20       Impact factor: 3.575

2.  A guanosine 3':5'-monophosphate-sensitive nuclease from Bacillus brevis.

Authors:  N Sarkar; H Paulus
Journal:  J Biol Chem       Date:  1975-01-25       Impact factor: 5.157

3.  Genetic control over the initiation of the synthesis of the short deoxynucleotide chains in E. coli.

Authors:  K G Lark
Journal:  Nat New Biol       Date:  1972-12-20

4.  Evidence for the direct involvement of RNA in the initiation of DNA replication in Escherichia coli 15T.

Authors:  K G Lark
Journal:  J Mol Biol       Date:  1972-02-28       Impact factor: 5.469

5.  Function of peptide antibiotics in sporulation.

Authors:  N Sarkar; H Paulus
Journal:  Nat New Biol       Date:  1972-10-25

6.  Mechanism of DNA chain growth. I. Possible discontinuity and unusual secondary structure of newly synthesized chains.

Authors:  R Okazaki; T Okazaki; K Sakabe; K Sugimoto; A Sugino
Journal:  Proc Natl Acad Sci U S A       Date:  1968-02       Impact factor: 11.205

7.  dnaG gene product, a rifampicin-resistant RNA polymerase, initiates the conversion of a single-stranded coliphage DNA to its duplex replicative form.

Authors:  J P Bouché; K Zechel; A Kornberg
Journal:  J Biol Chem       Date:  1975-08-10       Impact factor: 5.157

8.  A possible role for RNA polymerase in the initiation of M13 DNA synthesis.

Authors:  D Brutlag; R Schekman; A Kornberg
Journal:  Proc Natl Acad Sci U S A       Date:  1971-11       Impact factor: 11.205

9.  Initiation of deoxyribonucleic acid replication in a temperature-sensitive mutant of B. subtilis: evidence for a transcriptional step.

Authors:  S J Laurent
Journal:  J Bacteriol       Date:  1973-10       Impact factor: 3.490

10.  Hydroxyphenylazopyrimidines: characterization of the active forms and their inhibitory action on a DNA polymerase from Bacillus subtilis.

Authors:  J M Mackenzie; M M Neville; G E Wright; N C Brown
Journal:  Proc Natl Acad Sci U S A       Date:  1973-02       Impact factor: 11.205

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