Literature DB >> 6162672

Estrogenic inhibition of testicular growth by R2858 in preweanling rats.

J P Friend, M T Tseng.   

Abstract

Daily injections of physiologic doses of R2858 into preweanling rats from the 10th to the 19th day of age resulted in reduced testicular growth compared to controls. Body weights and other organ weights were unaffected. Leydig cells were smaller and less numerous, and showed distinct changes in ultrastructural morphology. Results of this study suggest that alpha-fetoprotein permits normal testicular development during postnatal life.

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Year:  1980        PMID: 6162672     DOI: 10.1007/BF01960138

Source DB:  PubMed          Journal:  Experientia        ISSN: 0014-4754


  12 in total

1.  EFFECT OF ESTROGEN OR TESTOSTERONE ON INITIATION AND MAINTENANCE OF SPERMATOGENESIS IN THE RAT.

Authors:  E STEINBERGER; G E DUCKETT
Journal:  Endocrinology       Date:  1965-06       Impact factor: 4.736

2.  The effect of hypophysectomy, cryptorchidism, estrogen and androgen upon the level of hyaluronidase in the rat testis.

Authors:  E STEINBERGER; W O NELSON
Journal:  Endocrinology       Date:  1955-04       Impact factor: 4.736

3.  Direct inhibitory effect of estrogen on Leydig cell function of hypophysectomized rats.

Authors:  A J Hsueh; M L Dufau; K J Catt
Journal:  Endocrinology       Date:  1978-10       Impact factor: 4.736

4.  Changes with age in levels of serum gonadotropins, prolactin and gonadal steroids in prepubertal male and female rats.

Authors:  K D Döhler; W Wuttke
Journal:  Endocrinology       Date:  1975-10       Impact factor: 4.736

5.  Ontogeny of 17beta-estradiol-binding protein in the female rat hypothalamus and anterior pituitary.

Authors:  J Spona; C Bieglmayer; D Adamiker; W Jettmar
Journal:  FEBS Lett       Date:  1977-04-15       Impact factor: 4.124

6.  An oestradiol receptor in rat testis interstitial tissue.

Authors:  A O Brinkmann; E Mulder; G J Lamers-Stahlhofen; M J Mechielsen; H J van der Molen
Journal:  FEBS Lett       Date:  1972-10-01       Impact factor: 4.124

Review 7.  Hormonal control of mammalian spermatogenesis.

Authors:  E Steinberger
Journal:  Physiol Rev       Date:  1971-01       Impact factor: 37.312

8.  Persistance of maternally derived 3H-estradiol in fetal and neonatal rats.

Authors:  J P Friend
Journal:  Experientia       Date:  1977-09-15

9.  [Submicroscopic changes in the Leydig cells of the rat testis following treatment with estrogens and following administration of gonadotropin].

Authors:  M Murakami; E Tonutti
Journal:  Endokrinologie       Date:  1966-12

10.  Effects of androgen and estradiol administration on the weight of the ventral prostate, seminal vesicles, and testes of immature rats.

Authors:  A C Jackson; M Tenniswood; C E Bird; A F Clark
Journal:  Invest Urol       Date:  1977-03
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