| Literature DB >> 6162104 |
A Vallbracht, J Treuner, B Flehmig, K E Joester, D Niethammer.
Abstract
During recent years clinical trials have shown that human leukocyte interferon (HuIFN-alpha) may be useful in the treatment of cancer, but very little has been done concerning the possible use of human fibroblast interferon (HuIFN-beta). Treuner et al. recently reported the successful treatment of a nasopharyngeal carcinoma with HuIFN-beta: in the course of IFN-therapy a HuIFN-beta neutralizing activity appeared in the serum of this patient. We report here that such activity is due to IgG antibodies--this study is the first to present evidence for antigenicity of IFN in a homologous system.Entities:
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Year: 1981 PMID： 6162104 DOI： 10.1038/289496a0
Source DB: PubMed Journal: Nature ISSN： 0028-0836 Impact factor: 49.962