Literature DB >> 6162101

Structural identification of the antibody-binding sites of Hong Kong influenza haemagglutinin and their involvement in antigenic variation.

D C Wiley, I A Wilson, J J Skehel.   

Abstract

Four 'antigenic sites' on the three-dimensional structure of the influenza haemagglutinin are identified. At least one amino acid substitution in each site seems to be required for the production of new epidemic strains between 1968 and 1975.

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Year:  1981        PMID： 6162101     DOI： 10.1038/289373a0

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   49.962


  579 in total

1.  N- and C-terminal residues combine in the fusion-pH influenza hemagglutinin HA(2) subunit to form an N cap that terminates the triple-stranded coiled coil.

Authors:  J Chen; J J Skehel; D C Wiley
Journal:  Proc Natl Acad Sci U S A       Date:  1999-08-03       Impact factor: 11.205

Review 2.  The evolution of human influenza viruses.

Authors:  A J Hay; V Gregory; A R Douglas; Y P Lin
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2001-12-29       Impact factor: 6.237

3.  Hemagglutinin 1-specific immunoglobulin G and Fab molecules mediate postattachment neutralization of influenza A virus by inhibition of an early fusion event.

Authors:  M J Edwards; N J Dimmock
Journal:  J Virol       Date:  2001-11       Impact factor: 5.103

Review 4.  Genetic subtypes, humoral immunity, and human immunodeficiency virus type 1 vaccine development.

Authors:  J P Moore; P W Parren; D R Burton
Journal:  J Virol       Date:  2001-07       Impact factor: 5.103

5.  Investigation of pathways for the low-pH conformational transition in influenza hemagglutinin.

Authors:  M Madhusoodanan; Themis Lazaridis
Journal:  Biophys J       Date:  2003-03       Impact factor: 4.033

6.  MF59 adjuvant enhances diversity and affinity of antibody-mediated immune response to pandemic influenza vaccines.

Authors:  Surender Khurana; Nitin Verma; Jonathan W Yewdell; Anne Katrin Hilbert; Flora Castellino; Maria Lattanzi; Giuseppe Del Giudice; Rino Rappuoli; Hana Golding
Journal:  Sci Transl Med       Date:  2011-06-01       Impact factor: 17.956

7.  Recognition of a single transmembrane degron by sequential quality control checkpoints.

Authors:  Laurence Fayadat; Ron R Kopito
Journal:  Mol Biol Cell       Date:  2003-03       Impact factor: 4.138

8.  Evolution of surface and nonstructural-1 genes of influenza B viruses isolated in the Province of Québec, Canada, during the 1998-2001 period.

Authors:  Yacine Abed; Michael B Coulthart; Yan Li; Guy Boivin
Journal:  Virus Genes       Date:  2003-10       Impact factor: 2.332

9.  Structural Insight into a Human Neutralizing Antibody against Influenza Virus H7N9.

Authors:  Cong Chen; Liguo Liu; Yan Xiao; Sheng Cui; Jianmin Wang; Qi Jin
Journal:  J Virol       Date:  2018-02-12       Impact factor: 5.103

Review 10.  Structural insights into the design of novel anti-influenza therapies.

Authors:  Nicholas C Wu; Ian A Wilson
Journal:  Nat Struct Mol Biol       Date:  2018-02-02       Impact factor: 15.369
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