Literature DB >> 6161947

Sensitisation to Mallory bodies (alcoholic hyalin) in alcoholic hepatitis.

S M Triggs, P R Mills, R N MacSween.   

Abstract

Using a leucocyte migration inhibition test sensitisation to Mallory bodies (alcoholic hyalin) was found in a statistically significant 41% of 17 patients with alcoholic hepatitis. Patients with alcohol-induced fatty liver and cirrhosis did not demonstrate sensitisation. Mallory bodies are a characteristic feature of alcohol-induced liver damage, and immunological sensitisation to them might lead to liver cell death and cell progression of the hepatitis process.

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Year:  1981        PMID: 6161947      PMCID: PMC1146402          DOI: 10.1136/jcp.34.1.21

Source DB:  PubMed          Journal:  J Clin Pathol        ISSN: 0021-9746            Impact factor:   3.411


  14 in total

Review 1.  Immunologic reactivity and alcoholic liver disease.

Authors:  R K Zetterman; C M Leevy
Journal:  Bull N Y Acad Med       Date:  1975-04

2.  In vitro and in vivo studies of cellular immunity in alcoholic cirrhosis.

Authors:  M R Berenyi; B Straus; D Cruz
Journal:  Am J Dig Dis       Date:  1974-03

3.  Studies in alcoholic liver disease in Britain. I. Clinical and pathological patterns related to natural history.

Authors:  P W Brunt; M C Kew; P J Scheuer; S Sherlock
Journal:  Gut       Date:  1974-01       Impact factor: 23.059

4.  Reduction in circulating T lymphocytes in alcoholic liver disease.

Authors:  I M Bernstein; K H Webster; R C Williams; R G Strickland
Journal:  Lancet       Date:  1974-08-31       Impact factor: 79.321

5.  Natural history of alcoholic hepatitis. I. The acute disease.

Authors:  M W Lischner; J F Alexander; J T Galambos
Journal:  Am J Dig Dis       Date:  1971-06

6.  Isolation and electrophoretic study on Mallory bodies from the livers of alcoholic cirrhosis.

Authors:  K Okamura; T R Harwood; H Yokoo
Journal:  Lab Invest       Date:  1975-08       Impact factor: 5.662

Review 7.  Liver disease of the alcoholic: role of immunologic abnormalities in pathogenesis, recognition, and treatment.

Authors:  C M Leevy; T Chen; A Luisada-Opper; N Kanagasundaram; R Zetterman
Journal:  Prog Liver Dis       Date:  1976

8.  Histocompatibility antigens, autoantibodies, and immunoglobulins in alcoholic liver disease.

Authors:  R J Bailey; N Krasner; A L Eddleston; R Williams; D E Tee; D Doniach; L A Kennedy; J R Batchelor
Journal:  Br Med J       Date:  1976-09-25

9.  Prognosis in acute liver disease of the alcoholic patient.

Authors:  W G Hardison; F I Lee
Journal:  N Engl J Med       Date:  1966-07-14       Impact factor: 91.245

10.  Lymphocyte cytotoxicity in alcoholic hepatitis.

Authors:  S Kakumu; C M Leevy
Journal:  Gastroenterology       Date:  1977-04       Impact factor: 22.682

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  2 in total

1.  Isolation of Mallory bodies and an attempt to demonstrate cell mediated immunity to Mallory body isolate in patients with alcoholic liver disease.

Authors:  C Gluud; F Hardt; J Aldershvile; P Christoffersen; H Lyon; J Nielsen
Journal:  J Clin Pathol       Date:  1981-09       Impact factor: 3.411

2.  Are antibodies to carbonic anhydrase II specific for anti-mitochondrial antibody-negative primary biliary cirrhosis?

Authors:  D Comay; K Cauch-Dudek; D Hemphill; E Diamandis; I Wanless; E J Heathcote
Journal:  Dig Dis Sci       Date:  2000-10       Impact factor: 3.199

  2 in total

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