Mannan-binding protein in lymphoid tissues of rats.

A binding protein which recognizes mannose and N-acetylglucosamine was isolated from mesenteric lymph nodes of rats by affinity chromatography. The isolated binding protein shares come common properties with liver mannan-binding protein: requirement of Ca2+ for the binding and high affinity for mannan. However, these two proteins were distinguishable by their antigenicity and their binding affinity for mannosamine.