Literature DB >> 6161689

Treatment of advanced untreated Hodgkin's disease with SCAB--an alternative to MOPP.

C H Diggs, P H Wiernik, J C Sutherland.   

Abstract

SCAB chemotherapy streptozocin (streptozotocin) lomustine (CCNU), doxorubicin hydrochloride (Adriamycin), and bleomycin sulfate was given in monthly courses to 20 patients with Stages IIIB, IVA, and IVB previously untreated Hodgkin's disease. Complete remissions were obtained in 15 (75%) of these patients, and partial remissions in two others. Toxicity of this program was acceptable. Although this study was not a direct comparison with MOPP, SCAB would appear to be at least as effective as MOPP and offers a reasonable alternative program for the patient with advanced stage, previously untreated Hodgkin's disease.

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Year:  1981        PMID： 6161689     DOI： 10.1002/1097-0142(19810115)47:2<224::aid-cncr2820470203>3.0.co;2-6

Source DB:  PubMed          Journal:  Cancer        ISSN： 0008-543X            Impact factor:   6.860


  4 in total

Review 1.  Current approaches to the treatment of advanced-stage Hodgkin's disease.

Authors:  J J Rusthoven
Journal:  CMAJ       Date:  1986-09-01       Impact factor: 8.262

Review 2.  Current management of Hodgkin's disease.

Authors:  B C Behrens; R C Young; V T DeVita
Journal:  Drugs       Date:  1985-10       Impact factor: 9.546

3.  Prognostic factors in COPP-treated patients with Hodgkin's disease.

Authors:  W Gassmann; L Perenyi; N Schmitz; W Kayser; H Pralle; H Löffler
Journal:  Blut       Date:  1982-06

4.  Long-term follow-up of advanced Hodgkin's disease patients treated with a combination of streptozotocin, lomustine (CCNU), doxorubicin and bleomycin (SCAB).

Authors:  P H Wiernik; C A Schiffer
Journal:  J Cancer Res Clin Oncol       Date:  1988       Impact factor: 4.553
  4 in total

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