Determination of the development time for the characterization of the nucleus formation in the argyrophil stainings.

Visual end-point "detection" is proposed for the determination of development time. One of adjacent sections is silverized up to an arbitrary intensity and the others treated in various manners for the investigation of certain processes of silver staining are developed until a given area of them equals in intensity, as "detected" by naked eye, with the same area of the control section. Due to the capacity of the human eye "to detect" identity or divergency accurately in light intensity, the error of development time does not exceed the value of 10%. Whereas, alterations of development time caused by the procedure tested mount up even to 300%.