Literature DB >> 6160262

Amino acid sequence analysis of reverse transcriptase subunits from avian myeloblastosis virus.

T D Copeland, D P Grandgenett, S Oroszlan.   

Abstract

The NH(2)-terminal amino acid sequences of the alpha and beta chains of avian myeloblastosis alphabeta DNA polymerase were determined by using microsequence analysis in the subnanomole range and were found to be identical up to 17 residues. The common sequence was as follows: Thr-Val-Ala-Leu-His-Leu-Ala-Ile-Pro-Leu-Lys-Trp-Lys-Pro-Asn-His-Thr-. This result provides convincing chemical evidence that the alpha chain is derived from the NH(2)-terminal region of the beta chain by proteolytic cleavage, whereas the amino acid composition for these alpha and beta subunits and p32 DNA endonuclease suggests that the latter is derived from the carboxyl-terminal region of the beta chain.

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Year:  1980        PMID： 6160262      PMCID： PMC353621          DOI： 10.1128/JVI.36.1.115-119.1980

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  27 in total

1.  Amino acid sequence homology of mammalian type C RNA virus major internal proteins.

Authors:  S Oroszlan; T Copeland; M R Summers; G Smythers; R V Gilden
Journal:  J Biol Chem       Date:  1975-08-25       Impact factor: 5.157

2.  Carboxypeptidase from yeast. Large scale preparation and the application to COOH-terminal analysis of peptides and proteins.

Authors:  R Hayashi; S Moore; W H Stein
Journal:  J Biol Chem       Date:  1973-04-10       Impact factor: 5.157

3.  Purification of the DNA polymerase of avian myeloblastosis virus.

Authors:  D L Kacian; K F Watson; A Burny; S Spiegelman
Journal:  Biochim Biophys Acta       Date:  1971-09-24

4.  A single subunit from avian myeloblastosis virus with both RNA-directed DNA polymerase and ribonuclease H activity.

Authors:  D P Grandgenett; G F Gerard; M Green
Journal:  Proc Natl Acad Sci U S A       Date:  1973-01       Impact factor: 11.205

5.  The low polarity of many membrane proteins.

Authors:  R A Capaldi; G Vanderkooi
Journal:  Proc Natl Acad Sci U S A       Date:  1972-04       Impact factor: 11.205

6.  Hemoglobin 3 chains in apes. Primary structures and the presumptive nature of back mutation in a normally silent gene.

Authors:  S H Boyer; A N Noyes; M L Boyer; K Marr
Journal:  J Biol Chem       Date:  1973-02-10       Impact factor: 5.157

7.  Studies on the reverse transcriptase of RNA tumor viruses. Structural relatedness of two subunits of avian RNA tumor viruses.

Authors:  W Gibson; I M Verma
Journal:  Proc Natl Acad Sci U S A       Date:  1974-12       Impact factor: 11.205

8.  Sequence relatedness between the subunits of avian myeloblastosis virus reverse transcriptase.

Authors:  H M Rho; D P Grandgenett; M Green
Journal:  J Biol Chem       Date:  1975-07-10       Impact factor: 5.157

9.  A protein sequenator.

Authors:  P Edman; G Begg
Journal:  Eur J Biochem       Date:  1967-03

10.  On the fidelity of DNA replication. Enzyme activities associated with DNA polymerases from RNA tumor viruses.

Authors:  G Seal; L A Loeb
Journal:  J Biol Chem       Date:  1976-02-25       Impact factor: 5.157
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  30 in total

1.  Ty3 integrase is required for initiation of reverse transcription.

Authors:  M Henrietta Nymark-McMahon; Nadejda S Beliakova-Bethell; Jean-Luc Darlix; Stuart F J Le Grice; Suzanne B Sandmeyer
Journal:  J Virol       Date:  2002-03       Impact factor: 5.103

2.  Role of the avian retroviral protease in the activation of reverse transcriptase during virion assembly.

Authors:  R C Craven; R P Bennett; J W Wills
Journal:  J Virol       Date:  1991-11       Impact factor: 5.103

3.  The chromodomain of Tf1 integrase promotes binding to cDNA and mediates target site selection.

Authors:  Atreyi Ghatak Chatterjee; Young Eun Leem; Felice D Kelly; Henry L Levin
Journal:  J Virol       Date:  2008-12-24       Impact factor: 5.103

4.  Proteolytic processing of avian sarcoma and leukosis viruses pol-endo recombinant proteins reveals another pol gene domain.

Authors:  F Alexander; J Leis; D A Soltis; R M Crowl; W Danho; M S Poonian; Y C Pan; A M Skalka
Journal:  J Virol       Date:  1987-02       Impact factor: 5.103

5.  Reverse transcriptase and protease activities of avian leukosis virus Gag-Pol fusion proteins expressed in insect cells.

Authors:  L Stewart; V M Vogt
Journal:  J Virol       Date:  1993-12       Impact factor: 5.103

6.  Mutations in nonconserved domains of Ty3 integrase affect multiple stages of the Ty3 life cycle.

Authors:  M H Nymark-McMahon; S B Sandmeyer
Journal:  J Virol       Date:  1999-01       Impact factor: 5.103

7.  Characterization of a transpositionally active Ty3 element and identification of the Ty3 integrase protein.

Authors:  L J Hansen; S B Sandmeyer
Journal:  J Virol       Date:  1990-06       Impact factor: 5.103

8.  Site-specific nicking at the avian retrovirus LTR circle junction by the viral pp32 DNA endonuclease.

Authors:  D P Grandgenett; A C Vora
Journal:  Nucleic Acids Res       Date:  1985-09-11       Impact factor: 16.971

9.  Nuclease mechanism of the avian retrovirus pp32 endonuclease.

Authors:  D P Grandgenett; A C Vora; R Swanstrom; J C Olsen
Journal:  J Virol       Date:  1986-06       Impact factor: 5.103

10.  Structure of glycosylated and unglycosylated gag polyproteins of Rauscher murine leukemia virus: carbohydrate attachment sites.

Authors:  A M Schultz; S M Lockhart; E M Rabin; S Oroszlan
Journal:  J Virol       Date:  1981-05       Impact factor: 5.103
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