Cerebral atrophy in end-stage uremia.

This study suggests that 1) cerebral atrophy is present in end-stage uremia; 2) the degree of atrophy correlates best with the age of onset of end-stage uremia and is most marked during the ages of cerebral development, but is also present in adults. Further studies will be needed to elucidate causative factor(s) and the degree of cerebral functional impairment, if any.