| Literature DB >> 6159993 |
Abstract
Calcium deprivation inhibits the formation and subsequent release of SRS-A as well as histamine from passively sensitized human lung fragments challenged with antigen. Antimycin A inhibits the release of histamine and SRS-A in a dose dependant fashion, while causing a mild inhibition of SRS-A formation throughout the dose range studied. These data suggest that the influx of calcium is the critical event for the generation of SRS-A within the cell.Entities:
Mesh：
Substances：
Year: 1980 PMID： 6159993 DOI： 10.1111/j.1365-2222.1980.tb02138.x
Source DB: PubMed Journal: Clin Allergy ISSN： 0009-9090