| Literature DB >> 6159950 |
Abstract
Two-day-old rats were pretreated with 50 mg/kg of capsaicin. After 3--4 months, specific binding of [3H]muscimol and [3H]strychnine was measured in membrane preparations from dorsal spinal cord. A 20-30% decrease of the number of [3H]muscimol binding sites was observed after capsaicin treatment. In contrast, [3H]strychnine binding was unchanged. The results provide indirect evidence for a presynaptic location of GABA receptors on capsaicin-sensitive primary afferent neurons.Entities:
Mesh：
Substances：
Year: 1980 PMID： 6159950 DOI： 10.1016/0006-8993(80)90160-2
Source DB: PubMed Journal: Brain Res ISSN： 0006-8993 Impact factor: 3.252