Literature DB >> 6158096

Effect of interferon-alpha 1 from E. coli on some cell functions.

M G Masucci, R Szigeti, E Klein, G Klein, J Gruest, L Montagnier, H Taira, A Hall, S Nagata, C Weissmann.   

Abstract

Interferon-alpha 1 from Escherichia coli transformed with a hybrid plasmid containing a human leukocyte complementary DNA insert, induces resistance to virus in appropriate target cells. It also shares the following properties with natural leukocyte interferon (IFN). (i) It enhances natural killing activity of human lymphocytes, (ii) it enhances antibody-dependent cell-mediated cytotoxicity, (iii) it suppresses antigen- and mitogen-induced leukocyte migration inhibition, (iv) it inhibits growth of IFN-sensitive Burkitt lymphoma cells. Since these activities are exhibited by a cloned protein species, they are due to IFN itself and not to other human proteins.

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Year:  1980        PMID： 6158096     DOI： 10.1126/science.6158096

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  14 in total

Review 1.  Combination strategies to enhance antitumor ADCC.

Authors:  Holbrook E Kohrt; Roch Houot; Aurélien Marabelle; Hearn Jay Cho; Keren Osman; Matthew Goldstein; Ronald Levy; Joshua Brody
Journal:  Immunotherapy       Date:  2012-05       Impact factor: 4.196

2.  Treatment with human recombinant leukocyte interferons inhibits in vitro invasive ability of human lung carcinoma cells.

Authors:  T J Ravine; N Ledinko
Journal:  Clin Exp Metastasis       Date:  1986 Jul-Sep       Impact factor: 5.150

Review 3.  Regulation of cell growth by interferon.

Authors:  M Shearer; J Taylor-Papadimitriou
Journal:  Cancer Metastasis Rev       Date:  1987       Impact factor: 9.264

4.  Interferon production by genetic engineering.

Authors: 
Journal:  Br Med J (Clin Res Ed)       Date:  1981-02-28

Review 5.  Interferons and interferon inducers: development of clinical usefulness and therapeutic promise.

Authors:  R B Pollard
Journal:  Drugs       Date:  1982 Jan-Feb       Impact factor: 9.546

6.  A species of human alpha interferon that lacks the ability to boost human natural killer activity.

Authors:  J R Ortaldo; R B Herberman; C Harvey; P Osheroff; Y C Pan; B Kelder; S Pestka
Journal:  Proc Natl Acad Sci U S A       Date:  1984-08       Impact factor: 11.205

7.  Constitutive production of human interferons by mouse cells with bovine papillomavirus as a vector.

Authors:  R Fukunaga; Y Sokawa; S Nagata
Journal:  Proc Natl Acad Sci U S A       Date:  1984-08       Impact factor: 11.205

8.  Comparison of intramuscular recombinant alpha interferon (rIFN-2A) with topical acyclovir for the treatment of first-episode herpes genitalis and prevention of recurrences.

Authors:  M J Levin; F N Judson; L Eron; Y J Bryson; L Corey; M Murray; R R Scheer
Journal:  Antimicrob Agents Chemother       Date:  1989-05       Impact factor: 5.191

9.  Target cell specificity of two species of human interferon-alpha produced in Escherichia coli and of hybrid molecules derived from them.

Authors:  M Streuli; A Hall; W Boll; W E Stewart; S Nagata; C Weissmann
Journal:  Proc Natl Acad Sci U S A       Date:  1981-05       Impact factor: 11.205

10.  Cocaine increases natural killer cell activity.

Authors:  C Van Dyke; A Stesin; R Jones; A Chuntharapai; W Seaman
Journal:  J Clin Invest       Date:  1986-04       Impact factor: 14.808
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