Literature DB >> 6157732

Purification of immunologically functional subsets of human Ia-like antigens on a monoclonal antibody (Q5/13) immunoadsorbent.

V Quaranta, L E Walker, M A Pellegrino, S Ferrone.   

Abstract

Serologic and immunochemical asays have shown that the monoclonal antibody Q5/13 recognizes an antigenic determinant expressed on a subset of human Ia-like antigens. Testing with a panel of HLA typed B lymphoid cells has shown that this determinant is different from those defining the serologic polymorphism of HLA-DR antigens. The monoclonal antibody Q5/13 has been used to purify subsets of human Ia-like antigens, which are immunologically functional. These reagents should facilitate the characterization of structural and functional properties of human Ia-like antigens.

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Year:  1980        PMID: 6157732

Source DB:  PubMed          Journal:  J Immunol        ISSN: 0022-1767            Impact factor:   5.422


  27 in total

1.  Activation of mononuclear cells by interleukin-12: an in vivo study in chimpanzees.

Authors:  F N Lauw; A A te Velde; P E Dekkers; P Speelman; J M Aerts; C E Hack; S J van Deventer; T van der Poll
Journal:  J Clin Immunol       Date:  1999-07       Impact factor: 8.317

2.  Direct binding of secreted T-cell receptor beta chain to superantigen associated with class II major histocompatibility complex protein.

Authors:  N R Gascoigne; K T Ames
Journal:  Proc Natl Acad Sci U S A       Date:  1991-01-15       Impact factor: 11.205

3.  Expression of HLA class I antigens on hepatocytes in liver disease.

Authors:  T Fukusato; M A Gerber; S N Thung; S Ferrone; F Schaffner
Journal:  Am J Pathol       Date:  1986-05       Impact factor: 4.307

4.  Abnormalities of T cells isolated from mediastinal lymph nodes and peripheral blood of patients with lung carcinoma: deficit in PHA-induced expression of HLA class II antigens and in autologous mixed lymphocyte reactions.

Authors:  F Indiveri; I Pierri; S Rogna; A Poggi; R Romano; A Tavano; G Ratto; G Motta; S Ferrone
Journal:  Cancer Immunol Immunother       Date:  1986       Impact factor: 6.968

5.  Distribution of antigenic determinants recognized by three monoclonal antibodies (Q2/70, Q5/6 and Q5/13) on human Ia-like alloantigens and on their subunits.

Authors:  V Quaranta; N Tanigaki; S Ferrone
Journal:  Immunogenetics       Date:  1981       Impact factor: 2.846

6.  Cross-reactivity between human and murine lymphocyte antigens. IV. Reactivity of H-2 alloantisera with HLA-A, B antigens.

Authors:  V Quaranta; M A Pellegrino; G N Callahan; S Ferrone
Journal:  Immunogenetics       Date:  1981       Impact factor: 2.846

7.  A monoclonal antibody to the HLA-DR product recognizes a polymorphic Ia determinant in mice.

Authors:  P M Brickell; I McConnell; C Milstein; B Wright
Journal:  Immunology       Date:  1981-07       Impact factor: 7.397

8.  The free and the beta 2-microglobulin-associated heavy chains of HLA-A, B alloantigens share the antigenic determinant recognized by the monoclonal antibody Q1/28.

Authors:  V Quaranta; L E Walker; G Ruberto; M A Pellegrino; S Ferrone
Journal:  Immunogenetics       Date:  1981       Impact factor: 2.846

9.  Reduction in susceptibility to natural killer cell-mediated lysis of human FO-1 melanoma cells after induction of HLA class I antigen expression by transfection with B2m gene.

Authors:  M Maio; M Altomonte; R Tatake; R A Zeff; S Ferrone
Journal:  J Clin Invest       Date:  1991-07       Impact factor: 14.808

10.  Cell surface properties of HLA antigens on Epstein-Barr virus-transformed cell lines.

Authors:  L M Smith; H R Petty; P Parham; H M McConnell
Journal:  Proc Natl Acad Sci U S A       Date:  1982-01       Impact factor: 11.205

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