Literature DB >> 6157091

A monoclonal antibody for large-scale purification of human leukocyte interferon.

D S Secher, D C Burke.   

Abstract

A clone of hybrid myelomas (NK2), secreting a mouse monoclonal antibody to human leukocyte interferon, has been isolated. The antibody neutralizes the antiviral activity of the interferon and, when covalently attached to a solid support and used as an immunoadsorbent, allows interferon purification of up to 5,000-fold in a single step.

Entities:  

Mesh：

Substances：

Year:  1980        PMID： 6157091     DOI： 10.1038/285446a0

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   49.962


  49 in total

Review 1.  Human biochemical genetics of enzyme proteins in the new age of molecular genetics.

Authors:  D M Swallow; D A Hopkinson
Journal:  J Inherit Metab Dis       Date:  1986       Impact factor: 4.982

Review 2.  Monoclonal antibodies in clinical medicine.

Authors:  H M Dick
Journal:  Br Med J (Clin Res Ed)       Date:  1985-09-21

3.  Monoclonal antibodies specific for simian virus 40 tumor antigens.

Authors:  E Harlow; L V Crawford; D C Pim; N M Williamson
Journal:  J Virol       Date:  1981-09       Impact factor: 5.103

4.  Interferon production by genetic engineering.

Authors: 
Journal:  Br Med J (Clin Res Ed)       Date:  1981-02-28

5.  Interferon research may be taking off.

Authors:  D A Tyrrell
Journal:  Arch Dis Child       Date:  1981-03       Impact factor: 3.791

6.  Interferon assay as a diagnostic test.

Authors:  R P Parry; J V Parry
Journal:  Lancet       Date:  1981-02-28       Impact factor: 79.321

7.  Monoclonal antibodies against murine gamma interferon.

Authors:  M Prat; G Gribaudo; P M Comoglio; G Cavallo; S Landolfo
Journal:  Proc Natl Acad Sci U S A       Date:  1984-07       Impact factor: 11.205

8.  Natural killer-cell activity, interferon-alpha 2 production, and interleukin-2 production in cyclosporine-treated and conventionally immunosuppressed human allograft recipients.

Authors:  P J Guillou; G R Giles; C W Ramsden
Journal:  J Clin Immunol       Date:  1986-09       Impact factor: 8.317

9.  Toxicity of interferon.

Authors:  G M Scott; D S Secher; D Flowers; J Bate; K Cantell; D A Tyrrell
Journal:  Br Med J (Clin Res Ed)       Date:  1981-04-25

10.  Sepharose-immobilized triazine dyes as adsorbants for human lymphoblastoid interferon purification.

Authors:  P J Neame; I Parikh
Journal:  Appl Biochem Biotechnol       Date:  1982-07       Impact factor: 2.926
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.