Literature DB >> 6154489

[Structure and function of DNA--membrane contact in cells].

B I Sukhorukov, V V Kuvichkin, L I Shabarchina.   

Abstract

A model of DNA-membrane contact based on the postulate about the determining role of membrane RNA (mbRNA) in providing its specifitity, stability and functional activity is proposed. Proceeding from the DNA-membrane contact structure, unity and interconditionality of reduplication and transcription processes are shown, and basic peculiarities of reduplication are discussed. It follows from the analysis of lysozyme-detergent treatment that two different DNA-membrane complex preparations can be obtained: one of these upon the spheroplast - "turned inside out spheroplast" transition, the other, containing specific DNA-membrane contact only - in the course of further detergent treatment. The parameters of the spheroplast - "turned inside out spheroplast" transition can be used to characterize the native DNA-membrane complex. It is concluded that RNA that stabilizes and makes the compact form of bacterial nucletide (f-DNA) is none other than the postulated mbRNA of the cellular DNA-membrane contact.

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Year:  1980        PMID: 6154489

Source DB:  PubMed          Journal:  Biofizika        ISSN: 0006-3029


  2 in total

1.  Isolation of chromatin DNA tightly bound to the nuclear envelope of HeLa cells.

Authors:  Vasily Vladimirovich Kuvichkin
Journal:  J Membr Biol       Date:  2012-05-30       Impact factor: 1.843

2.  DNA-induced aggregation and fusion of phosphatidylcholine liposomes in the presence of multivalent cations observed by the cryo-TEM technique.

Authors:  Vasily V Kuvichkin; Radostin S Danev; Hideki Shigematsu; Kuniaki Nagayama
Journal:  J Membr Biol       Date:  2009-01-03       Impact factor: 1.843

  2 in total

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