Literature DB >> 6154151

Inhibition of herpes simplex virus type 2-induced biochemical transformation by interferon.

F Rapp, Y Nishiyama.   

Abstract

The effect of interferon on the biochemical transformation of thymidine kinase-deficient cells by UV-inactivated herpes simplex virus type 2 has been studied. Transformation was much less sensitive to the action of interferon than virus multiplication. However, the continuous presence of a high dose of interferon (2,000 U) inhibited transformation almost completely. Although we could not differentiate between the effect of interferon on fixation and expression of the virus thymidine kinase gene, data suggest that the inhibitory effect of interferon on transformation might be partially due to the suppression of virus thymidine kinase expression.

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Year:  1980        PMID： 6154151      PMCID： PMC288570          DOI： 10.1128/JVI.33.1.543-546.1980

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  20 in total

1.  Clinical and laboratory investigations on man: systemic administration of potent interferon to man.

Authors:  H Strander; K Cantell; G Carlström; P A Jakobsson
Journal:  J Natl Cancer Inst       Date:  1973-09       Impact factor: 13.506

Review 2.  An analysis of seroepidemiological studies of herpesvirus type 2 and carcinoma of the cervix.

Authors:  W E Rawls; E Adam; J L Melnick
Journal:  Cancer Res       Date:  1973-06       Impact factor: 12.701

3.  Oncogenic transformation of hamster cells after exposure to herpes simplex virus type 2.

Authors:  R Duff; F Rapp
Journal:  Nat New Biol       Date:  1971-09-08

4.  Inhibitory effect of interferon on murine sarcoma and leukaemia virus infection in vitro.

Authors:  P S Sarma; G Shiu; S Baron; R J Huebner
Journal:  Nature       Date:  1969-08-23       Impact factor: 49.962

5.  The effect of interferon on SV-40 T antigen production in SV-40-transformed cells.

Authors:  M N Oxman; S Baron; P H Black; K K Takemoto; K Habel; W P Rowe
Journal:  Virology       Date:  1967-05       Impact factor: 3.616

6.  Cell growth and the initiation of transformation by SV40.

Authors:  G J Todaro; H Green
Journal:  Proc Natl Acad Sci U S A       Date:  1966-02       Impact factor: 11.205

7.  The role of interferon in the inhibition of SV40 transformation of mouse cell line 3T3.

Authors:  G J Todaro; S Baron
Journal:  Proc Natl Acad Sci U S A       Date:  1965-09       Impact factor: 11.205

8.  Transfer of thymidine kinase to thymidine kinaseless L cells by infection with ultraviolet-irradiated herpes simplex virus.

Authors:  W Munyon; E Kraiselburd; D Davis; J Mann
Journal:  J Virol       Date:  1971-06       Impact factor: 5.103

9.  Interferon and transcription of early virus-specific RNA in cells infected with simian virus 40.

Authors:  M N Oxman; M J Levin
Journal:  Proc Natl Acad Sci U S A       Date:  1971-02       Impact factor: 11.205

10.  Properties of hamster embryo fibroblasts transformed in vitro after exposure to ultraviolet-irradiated herpes simplex virus type 2.

Authors:  R Duff; F Rapp
Journal:  J Virol       Date:  1971-10       Impact factor: 5.103
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  1 in total

1.  Sensitivity in vitro of herpes simplex virus isolates to human fibroblast interferon.

Authors:  S Leventon-Kriss; M Movshovitz; Z Smetana; M Shewach-Millet; T Doerner; T Gotlieb-Stematsky
Journal:  Med Microbiol Immunol       Date:  1987       Impact factor: 3.402
  1 in total

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