Literature DB >> 6153758

Bleomycin-induced structural chromosomal aberrations in spermatogonia and bone-marrow cells of mice.

P P van Buul, J H Goudzwaard.   

Abstract

The induction of structural chromosomal aberrations by bleomycin (BLM) was studied in bone-marrow cells and spermatogonia of the mouse at doses of 10, 20, 40 and 80 mg/kg. BLM induced genetically important reciprocal translocations in stem-cell spermatogonia as measured with the spermatocyte test, and the response of bone-marrow cells to BLM was not markedly different from that of spermatogonia.

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Year:  1980        PMID: 6153758     DOI: 10.1016/0027-5107(80)90096-2

Source DB:  PubMed          Journal:  Mutat Res        ISSN: 0027-5107            Impact factor:   2.433


  5 in total

1.  Highly conservative reciprocal translocations formed by apparent joining of exchanged DNA double-strand break ends.

Authors:  P Wang; R H Zhou; Y Zou; C K Jackson-Cook; L F Povirk
Journal:  Proc Natl Acad Sci U S A       Date:  1997-10-28       Impact factor: 11.205

2.  Bleomycin-induced chromosomal aberrations and sister chromatid exchanges in Down lymphocyte cultures.

Authors:  K Iijima; K Morimoto; A Koizumi; M Higurashi; M Hirayama
Journal:  Hum Genet       Date:  1984       Impact factor: 4.132

Review 3.  Recovery of Spermatogenesis Following Cancer Treatment with Cytotoxic Chemotherapy and Radiotherapy.

Authors:  Keisuke Okada; Masato Fujisawa
Journal:  World J Mens Health       Date:  2018-11-27       Impact factor: 5.400

Review 4.  Genetic anomalies in mammalian germ cells and their significance for human reproductive and developmental risk.

Authors:  V L Dellarco
Journal:  Environ Health Perspect       Date:  1993-07       Impact factor: 9.031

Review 5.  Current practices in fertility preservation in male cancer patients.

Authors:  E Charles Osterberg; Ranjith Ramasamy; Puneet Masson; Robert E Brannigan
Journal:  Urol Ann       Date:  2014-01
  5 in total

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