| Literature DB >> 6153758 |
Abstract
The induction of structural chromosomal aberrations by bleomycin (BLM) was studied in bone-marrow cells and spermatogonia of the mouse at doses of 10, 20, 40 and 80 mg/kg. BLM induced genetically important reciprocal translocations in stem-cell spermatogonia as measured with the spermatocyte test, and the response of bone-marrow cells to BLM was not markedly different from that of spermatogonia.Entities:
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Year: 1980 PMID: 6153758 DOI: 10.1016/0027-5107(80)90096-2
Source DB: PubMed Journal: Mutat Res ISSN: 0027-5107 Impact factor: 2.433